孕晚期血浆凝血因子、D-二聚体水平对妊娠期糖尿病患者的临床意义  

Clinical Significance of Plasma Coagulation Factors and D-dimer Levels in the Third Trimester for Gestational Diabetes Patients

作　　者：李晶晶 Li Jingjing(Department of Laboratory Medicine,Kaifeng Maternity Hospital,Kaifeng 475000)

机构地区：[1]开封市妇产医院检验科,开封475000

出　　处：《数理医药学杂志》2021年第7期987-988,共2页Journal of Mathematical Medicine

摘　　要：目的:探讨孕晚期血浆凝血因子、D-二聚体水平对妊娠期糖尿病患者的临床意义。方法:选择某院收治的妊娠期糖尿病孕妇88例作为观察组,正常妊娠孕妇88例作为对照组,对比两组的凝血功能及D-二聚体水平。结果:观察组的凝血酶时间(TT)、凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)分别为(11.19±1.75)s、(12.23±2.01)s、(28.92±2.93)s,明显低于对照组的(13.38±1.03)s、(17.31±1.96)s、(35.82±1.85)s;观察组纤维蛋白原(FIB)与D-二聚体(D-D)分别为(5.08±0.81)g/L、(0.95±0.29)mg/L,明显高于对照组的(2.57±0.73)g/L、(0.27±0.04)mg/L,差异均具有统计学意义(P<0.05)。结论:对妊娠晚期孕妇的凝血四项及D-D水平进行检测,观察其凝血功能状态及相关指标水平,对于孕晚期产妇而言具有重要的意义。Objective:To investigate the clinical significance of plasma coagulation factors and D-dimer levels in patients with gestational diabetes during the third trimester.Methods:Eighty-eight pregnant women with gestational diabetes who were treated in a hospital were selected as the observation group,and 88 normal pregnant women were used as the control group.The coagulation function and D-dimer levels of the two groups were compared.Results:The thrombin time(TT),prothrombin time(PT),and activated partial thromboplastin time(APTT)in the observation group were(11.19±1.75)s,(12.23±2.01)s,and(28.92±2.93)s,which were significantly lower than those in the control group[(13.38±1.03)s,(17.31±1.96),(35.82±1.85)s];The fibrinogen(FIB)and D-dimer(DD)in the observation group were(5.08±0.81)g/L and(0.95±0.29)mg/L,which were significantly higher than(2.57±0.73)g/L and(0.27±0.04)mg/L in the control group;and the difference was statistically significant(P<0.05).Conclusion:The detection of the four coagulation and D-D levels in late pregnant women,and the observation of their coagulation function status and related index levels are of great significance for late pregnant women.

关 键 词：孕晚期 血浆凝血因子 D-二聚体 妊娠期糖尿病 

分 类 号：R714.25[医药卫生—妇产科学]