食管钡餐造影+CT对食管癌放疗患者近期疗效及预后评估的价值研究  

The Value of Barium Esophagography Combined with CT in the Evaluation of Short-term Efficacy and Prognosis of Radiotherapy for Esophageal Cancer

作　　者：张星元 张进安 王三平 Zhang Xing-yuan;Zhang Jin-an;Wang San-ping(Department of Oncology,the First People's Hospital of Wudu District,Longnan 746000,GansuProvince,China;Department of Tumor Radiotherapy,the First People's Hospital of Wudu District,Longnan746000,Gansu Province,China)

机构地区：[1]甘肃省陇南市武都区第一人民医院肿瘤科,甘肃陇南746000 [2]甘肃省陇南市武都区第一人民医院肿瘤放射治疗科,甘肃陇南746000

出　　处：《中国CT和MRI杂志》2021年第8期82-85,共4页Chinese Journal of CT and MRI

摘　　要：目的探究食管钡餐造影+CT在食管癌放疗患者近期疗效及预后评估中的应用价值。方法对我院2013年3月至2019年3月期间收治的105例食管癌放疗患者相关资料进行回顾性分析,患者在治疗前后以及复查均接受食管钡餐造影以及CT扫描检查,评估其对患者近期疗效及预后评估价值。结果放疗后CT扫描检查淋巴结长径、短径以及体积均显著低于放疗前(P<0.05);钡餐造影结果显示105例患者总缓解率为88.57%(93/105),1年生存率为80.95%(85/105);疗效良好组患者放疗后淋巴结长径、短径以及体积显著低于疗效不佳组(P<0.05);预后良好组患者放疗后淋巴结长径、短径以及体积显著低于预后不佳组,总缓解率显著高于预后不佳组(P<0.05);多元Logistics回归分析结果显示淋巴结长径、短径以及体积是影响患者近期疗效独立危险因素(P<0.05),淋巴结长径、短径以及体积、总缓解率是影响患者预后独立危险因素(P<0.05);ROC曲线显示淋巴结长径、短径以及体积预测患者近期疗效AUC分别为0.664、0.618、0.813(P<0.05),淋巴结长径、短径以及体积预测患者预后AUC分别为0.641、0.652、0.836(P<0.05)。结论食管钡餐造影+CT用于评估食管癌患者近期疗效以及预后情况价值优异。Objective To explore the value of barium esophagography combined with CT in the evaluation of short-term efficacy and prognosis of radiotherapy for esophageal cancer.Methods The relevant data of 105 patients undergoing radiotherapy for esophageal cancer in the hospital between March 2013 and March 2019 were retrospectively analyzed.All patients completed barium esophagography and CT scan before and after treatment.The value of barium esophagography combined with CT in the evaluation of short-term efficacy and prognosis was evaluated.Results After radiotherapy,the lymph node length diameter,short diameter and volume measured by CT were significantly smaller than those before radiotherapy(P<0.05).Barium esophagography results showed that the total response rate of the 105 patients was 88.57%(93/105),and the 1-year survival rate was 80.95%(85/105).The lymph node length diameter,short diameter and volume in the good efficacy group after radiotherapy were significantly smaller than those in the poor efficacy group(P<0.05).The above indexes in the good prognosis group were significantly smaller than those in the poor prognosis group,and the total response rate was significantly higher than the poor prognosis group(P<0.05).The results of multivariate Logistic regression analysis showed that the lymph node length diameter,short diameter and volume were independent risk factors affecting the short-term efficacy and prognosis(P<0.05).ROC curve analysis showed that the areas under curves of the lymph node length diameter,short diameter and volume for predicting the short-term efficacy were 0.664,0.618,and 0.813,respectively(P<0.05).The areas under curves for predicting the prognosis were 0.641,0.652,and 0.836,respectively(P<0.05).Conclusion Barium esophagography combined with CT has great value in evaluating the short-term efficacy and prognosis of patients with esophageal cancer.

关 键 词：食管钡餐造影+CT 食管癌放疗患者 近期疗效 预后 评估价值 

分 类 号：R445.3[医药卫生—影像医学与核医学] R735.1[医药卫生—诊断学]