能谱CT多参数成像在胃腺癌分化程度中的应用价值  

Application Value of Energy Spectrum CT Multi-parameter Imaging in Differentiation of Gastric Adenocarcinoma

作　　者：李长健 朱广辉[1] LI Chang-jian;ZHU Guang-hui(Department of Radiology,the First Affiliated Hospital of Bengbu Medical College,Bengbu 233000,Anhui Province,China)

机构地区：[1]蚌埠医学院第一附属医院放射科,安徽蚌埠233000

出　　处：《中国CT和MRI杂志》2021年第8期133-135,162,共4页Chinese Journal of CT and MRI

摘　　要：目的通过对不同分化程度胃腺癌在能谱CT成像上的参数及特征进行对比分析,研究CT能谱成像在胃腺癌诊断中的应用价值。方法选择60例胃腺癌影像资料进行回顾性分析,将其依据分化程度进行分组,其中低分化组26例,中高分化组34例,全部研究对象都进行CT能谱平扫及动静脉双期扫描。得到图像后确定出感兴趣区域,对所得结果进行处理,计算出不同扫描期相所有病灶在不同单能量水平下CT值、碘-水浓度等相关参数,并进行独立样本t检验。结果静脉期40~90keV各单能量水平下低分化组的CT值均高于中高分化组,静脉期低分化组标准化碘基值(0.49±0.14)高于中高分化组(0.39±0.06),动脉期仅60keV单能量水平CT值低分化组(79.47±13.80)高于中高分化组(67.35±13.20),差异具有统计学意义(P<0.05);余平扫及动静脉双期相关的参数差异小,不存在统计学意义。结论能谱CT多参数成像能够对组织病变进行定量分析,40~90keV下单能量CT值及标准化碘浓度有助于术前胃癌分化程度评估。Objective To study the diagnostic value of energy spectrum CT in gastric adenocarcinoma by comparing the parameters and characteristics of different differentiation degrees of gastric adenocarcinoma.Methods The imaging data of 60 cases of gastric adenocarcinoma were retrospectively analyzed and divided into groups according to the degree of differentiation,including 26 cases in the low-differentiation group and 34 cases in the middle-differentiation group.All the subjects underwent CT energy spectrum plain scan and arteriovenous double-phase scan.After the image was obtained,the region of interest was determined,the results were processed,and relevant parameters such as CT value and iodide-water concentration of all lesions in different scanning phases at different single energy levels were calculated,and independent sample T-test was conducted.Results Venous phase of 40-90 keV CT values of each single energy levels and low differentiation group were higher than in high differentiation group,venous phase of low differentiation standardized iodine group base value (0.49±0.14) is higher than that in high differentiation group (0.39±0.06),60keV one energy level only CT arterial values low differentiation (79.47±13.80) is higher than the high differentiation group (67.35±13.20),statistically significant difference,statistically significant difference (P<0.05);There was no statistical significance in the difference of parameters related to residual sweep and arteriovenous double stages.Conclusion Energy spectrum CT multi-parameter imaging can be used for quantitative analysis of tissue lesions,and 40-90keV single-energy CT value and standardized iodine concentration are helpful for preoperative evaluation of gastric cancer differentiation degree.

关 键 词：X线计算机 能谱成像 胃腺癌 分化程度 

分 类 号：R322.44[医药卫生—人体解剖和组织胚胎学] R445.3[医药卫生—基础医学]