琼海地区育龄女性PCOS患病调查及危险因素分析  

The prevalence survey and risk factors analysis of PCOS among women of childbearing age in Qionghai

作　　者：杨丽玫 王小蔓 蔡余 王冰[1] YANG Limei;WANG Xiaoman;CAI Yu;WANG Bing(Qionghai Hospital of Traditional Chinese Medicine,Hainan Province,571400)

机构地区：[1]海南省琼海市中医院,571400

出　　处：《中国计划生育学杂志》2021年第5期881-884,共4页Chinese Journal of Family Planning

基　　金：海南省自然科学基金青年基金项目(819QN372)。

摘　　要：目的:调查琼海地区育龄女性多囊卵巢综合征(PCOS)患病情况及相关危险因素。方法:采用流行病学随机抽样调查方法,于2018年1月-2020年1月在琼海地区随机抽取1600名20~45岁育龄女性进行PCOS患病调查,筛查确诊PCOS病例为PCOS组,余为非PCOS组,比较两组基线资料并分析PCOS危险因素。结果:收回有效问卷1572份(98.3%),确诊PCOS 95例,患病率6.0%。PCOS患者中临床表现从高到低依次为腰围>80cm(39.0%)、痤疮(34.7%)、闭经(26.3%)、月经稀发(25.3%)、超重(24.2%)、不孕(22.1%)、多毛(23.2%)、肥胖(6.3%)。多因素logistic回归分析显示,家族糖尿病史、月经初潮时间提前或推迟、母亲不孕、体质指数高是育龄女性PCOS患病的危险因素(P<0.05)。结论:琼海地区育龄女性PCOS患病率为6.0%,临床表现以月经稀发、闭经、不孕、痤疮、多毛、肥胖为主,家族糖尿病史、月经初潮时间提前或推迟、母亲不孕、体质指数高是育龄女性PCOS患病危险因素。提示当地应针对这一特点进行防治。Objective: To investigate the prevalence and risk factors of polycystic ovary syndrome(PCOS) among women of childbearing age in Qionghai area. Methods: The epidemiological random sampling method was used for PCOS investigation by randomly selected 1600 childbearing age women aged 20-45 years in Qionghai area from January 2018 to January 2020. The women with confirmed PCOS were included in study group and the other women were included in control group. The baseline data of the women were compared between the two groups, and the risk factors of PCOS were analyzed. Results: 1572(98.3%) valid questionnaires were returned, 95 women with PCOS were confirmed with 6.0% prevalence. Among the women with PCOS, the percentage of clinical manifestations from high to low was waist circumference >80 cm(38.95%), acne(34.7%), amenorrhea(26.3%), menstruation(25.3%), overweight(24.2%), infertility(22.1%), hypertrichosis(23.2%), and obesity(6.3%). Multivariate logistic regression analysis showed that family history of diabetes, early or late menarche, maternal infertility, and high body mass index were the risk factors of childbearing age women with PCOS(P<0.05). Conclusion: The clinical manifestations of childbearing age women with PCOS in Qionghai area are mainly irregular menstruation, amenorrhea, infertility, acne, hirsute, and obesity. Family history of diabetes, early or late menarche, maternal infertility and high body mass index are the risk factors of childbearing age women with PCOS. It is suggested that the prevention and control measurement for PCOS should be carried out based on these characteristics.

关 键 词：琼海地区 育龄妇女 多囊卵巢综合征 患病率 流行病学调查 危险因素 

分 类 号：R711.75[医药卫生—妇产科学]