高雌二醇片/雌二醇地屈孕酮片应用于稽留流产术后恢复效果  

Effect of high estradiol tablets or estradiol and dicrogesterone tablets treatment for the postoperative recovery of women with missed abortion

作　　者：李岩[1] 梁琛[1] 南燕燕 高瑞雪 刘晓华 LI Yan;LIANG Chen;NAN Yanyan;GAO Ruixue;LIU Xiaohua(The Second People's Hospital of Hengshui,Hebei Province,053000)

机构地区：[1]河北省衡水市第二人民医院,053000

出　　处：《中国计划生育学杂志》2021年第5期914-916,920,共4页Chinese Journal of Family Planning

基　　金：衡水市科技计划项目(2019014015Z)。

摘　　要：目的:观察高雌二醇片/雌二醇地屈孕酮片在行稽留流产术后恢复、并发症和不良反应效果。方法:选择2019年1月-2020年1月在本院行清宫术的150例稽留流产患者,根据用药不同分为观察组和对照组各75例。观察组采用高雌二醇片/雌二醇地屈孕酮片,对照组服用新生化颗粒。比较两组患者术后阴道出血情况、腹痛、术后两周子宫内膜厚度、月经恢复情况及并发症等。结果:观察组治疗后出血时间(4.4±1.4d)、出血量(35.2±3.4ml)、月经复潮(31.3±4.3d)和腹痛持续时间(27.3±6.0min)均低于对照组(P<0.05),子宫内膜厚度(5.2±2.0mm)与对照组无差异(P>0.05);两组均有下腹痛、经量减少以及阴道分泌物增多,观察组盆腔感染及经量减少的发生率(13.3%)低于对照组(24.0%)(P<0.05)。结论:稽留流产术后应用高雌二醇片/雌二醇地屈孕酮片能有效加快术后患者月经恢复、降低出血量,不良反应较轻。Objective: To observe the clinical effects of high estradiol tablets or estradiol and dicrogesterone tablets treatment on postoperative recovery, complications, and adverse reactions of women with missed abortion. Methods: 150 women with missed abortion who underwent curettage were selected as the observation objects from January 2019 to January 2020. According to different postoperative medication, these women were divided into observation group and control group(75 cases in each group). The women in the observation group were given high estradiol tablets or estradiol and dicrogesterone tablets, and the women in the control group were given new shenghua granules. The total amount of postoperative vaginal bleeding, the duration of abdominal pain, the endometrial thickness in postoperative 2 weeks, the situation of menstrual recovery, and the complications rate of the women were compared between the two groups. Results: After treatment, the duration of bleeding(4.4±1.4 d), the amount of bleeding(35.2±3.4 ml), the time of menstruation recovery(31.3±4.3 d), and the duration of abdominal pain(27.3±6.0 min) of the women in the observation group were significant lower than those of the women in the control group(P<0.05), but the endometrial thickness(5.2±2.0 mm) of the women in the observation group had no significant different from that of the women in the control group(P>0.05). There were women with lower abdominal pain, decreased menstrual volume, or increased vaginal discharge in both groups. The incidence of pelvic infection and decreased menstrual volume(13.3%) of the women in the observation group was significant lower than that(24.0%) of the women in the control group(P<0.05). Conclusion: The application of high estradiol tablets or estradiol and dicrogesterone tablets for treating the women with missed abortion can effectively accelerate the menstrual recovery, reduce the amount of postoperative bleeding, and reduce the adverse reactions.

关 键 词：稽留流产 术后恢复 高雌二醇片/雌二醇地屈孕酮片 

分 类 号：R713.41[医药卫生—妇产科学]