具有过氧化物酶活性的纳米材料在比色葡萄糖生物传感器中的应用进展  

Application progress of nanomaterial with peroxidase activity in colorimetric glucose biosensor

作　　者：喻昌木 张荣 卢小鸾 孙晓霞 杨敏[1] 彭黔荣 Yu Changmu;Zhang Rong;Lu Xiaoluan;Sun Xiaoxia;Yang Min;Peng Qianrong(School of Pharmacy,Guizhou University,Guiyang 550025;College of Chemistry and Chemical Engineering,Guizhou University,Guiyang 550025;Technology Center of Guizhou China Tobacco Industry Co.,Ltd.,Guiyang 550009)

机构地区：[1]贵州大学药学院,贵阳550025 [2]贵州大学化学与化工学院,贵阳550025 [3]贵州中烟工业有限责任公司技术中心,贵阳550009

出　　处：《化工新型材料》2021年第6期226-230,共5页New Chemical Materials

基　　金：国家自然科学基金(21562014);贵州中烟科技项目(黔烟工技[2015]8号)。

摘　　要：葡萄糖是细胞常见的代谢中间体和主要能量来源,而葡萄糖的含量是低血糖和糖尿病的重要指标。糖尿病是一种常见的代谢障碍疾病,为避免进一步的并发症,应严格监测糖尿病患者的血糖水平。与天然酶相比,纳米材料模拟酶具有催化活性高,稳定性好,成本低等特点。近年来,纳米材料作为过氧化物模拟酶检测葡萄糖和过氧化氢含量受到了关注。因此,综述了金属氧化物纳米材料、贵金属纳米材料以及金属有机框架纳米材料在比色葡萄糖生物传感器中的应用进展,并对未来发展方向进行展望。Glucose is a common metabolic intermediate and main energy source for cells,and glucose content is an important indicator of hypoglycemia and diabetes.Diabetes is a common metabolic disorder.To avoid further complications,the blood glucose level of diabetic patients should be strictly monitored.Compared with natural enzymes,nanomaterials mimic enzymes have the characteristics of high catalytic activity,good stability and low cost.In recent years,nanomaterials have received widespread attention as peroxide analog enzymes for glucose and hydrogen peroxide detection.Therefore,the application progress of metal oxide nanomaterials,precious metal nanomaterials and metalorganic framework nanomaterials colorimetric glucose biosensors were reviewed,and prospected the future development direction.

关 键 词：纳米材料 过氧化物酶 比色法 生物传感器 葡萄糖 

分 类 号：O657[理学—分析化学]