升清化浊法组方内服联合中药直肠点滴及普济痔疮栓治疗肛窦炎疗效观察  

Efficacy of the decoction of Shengqing Huazhuo method,rectal drip of Chinese medicine combined with Puji hemorrhoid suppository on anal sinusitis

作　　者：沙静涛 范丽颖 张新 赵伟 黄蓓 SHA Jingtao;FAN Liying;ZHANG Xin;ZHAO Wei;HUANG Bei(Xi’an Hospital of Chinese Medicine,Xi’an 710021,Shaanxi,China)

机构地区：[1]西安市中医医院,陕西西安710021

出　　处：《现代中西医结合杂志》2021年第19期2053-2057,共5页Modern Journal of Integrated Traditional Chinese and Western Medicine

基　　金：陕西省中医药管理局中医药科研计划项目(LCPT058)。

摘　　要：目的观察升清化浊法、中药直肠点滴联合普济痔疮栓治疗肛窦炎的疗效及对免疫功能的影响。方法选取2018年3月—2020年3月在西安市中医医院治疗的肛窦炎患者140例,随机分为4组各35例。对照1组给予升清化浊法组方内服及普济痔疮栓肛内留置治疗,对照2组给予中药直肠点滴及普济痔疮栓肛内留置治疗,对照3组给予微波治疗及普济痔疮栓肛内留置治疗,观察组给予升清化浊法组方内服、中药直肠点滴及普济痔疮栓肛内留置,均治疗10 d。观察4组的疗效、中医症状评分、免疫功能,比较4组治疗3个月后复发率。结果观察组总有效率为94.3%(33/35),显著高于各对照组(P均<0.05),各对照组间比较差异均无统计学意义(P均>0.05)。治疗后,4组中医症状评分、CD8^(+)均显著降低(P均<0.05),且观察组显著低于各对照组(P均<0.05);4组CD3^(^(+))、CD4^(+)均显著升高(P均<0.05),且观察组显著高于各对照组(P均<0.05);各对照组之间上述指标比较差异均无统计学意义(P均>0.05)。随访3个月后,观察组复发率为3.0%(1/33),对照1组复发率为4.0%(1/25),对照2组复发率为7.7%(2/26),对照3组复发率为9.1%(2/22),4组复发率比较差异无统计学意义(P均>0.05)。结论升清化浊法组方内服、中药直肠点滴联合普济痔疮栓治疗肛窦炎疗效显著,能够明显减轻患者的临床症状与体征,改善患者免疫功能,且复发率低。Objective It is to observe the effect of Shengqing Huazhuo method,Chinese medicine rectal drip combined with Puji hemorrhoid suppository in the treatment of anal sinusitis and its influence on immune function.Methods A total of 140 patients with anal sinusitis treated in Xi’an Hospital of Traditional Chinese Medicine from March 2018 to March 2020 were selected and randomly divided into 4 groups with 35 cases in each group.The control groupⅠwas given the the decoction based on Shengqing Huazhuo method orally and Puji hemorrhoid suppository indwelling in the anus,the control groupⅡwas given Chinese medicine rectal drip and Puji hemorrhoid suppository indwelling in the anus,and the control groupⅢwas given microwave therapy and Puji hemorrhoid suppository indwelling in the anal,the observation group was given the decoction based on Shengqing Huazhuo method orally,rectal infusion of traditional Chinese medicine,and Puji hemorrhoid suppository indwelling in the anus,all of which were treated for 10 days.The efficacy,TCM symptom score,and immune function of the 4 groups were observed,and the recurrence rate of the 4 groups after 3 months was compared.Results The total effective rate of the observation group was 94.3%(33/35),which was significantly higher than those of the control groups(P<0.05),there was no statistically significant difference between the control groups(P>0.05).After treatment,the scores of TCM symptoms and CD8^(+)in the 4 groups were significantly reduced(all P<0.05),and the observation group was significantly lower than those in the control group(P<0.05);the CD3^(+)and CD4^(+)in the 4 groups were significantly increased,and the observation group was significantly higher than those in the control groups(P<0.05),there was no statistically significant difference in the above indicators among the control groups(P>0.05).After 3 months of follow-up,the recurrence rate of the observation group was 2.9%(1/33),the recurrence rate of the control groupⅠwas 4.0%(1/25),the recurrence rate of the control

关 键 词：肛窦炎 升清化浊法 中药直肠点滴 普济痔疮栓 免疫功能 

分 类 号：R657.1[医药卫生—外科学]