阿尔茨海默病伴吞咽障碍患者两种鼻饲肠内营养支持方法及并发症状况分析  

Two Methods of Enteral Nutrition Support by Nasal Feeding and Analysis of Complications in Patients with Alzheimer's Disease and Dysphagia

作　　者：陈萌[1] CHEN Meng(Department of Internal Medicine,Suzhou University Hospital,Suzhou,Jiangsu Province,215123 China)

机构地区：[1]苏州大学医院内科,江苏苏州215123

出　　处：《系统医学》2021年第9期57-59,共3页Systems Medicine

摘　　要：目的探讨两种鼻饲肠内营养支持方法对阿尔茨海默病伴吞咽障碍患者的影响以及并发症情况分析。方法选取2017年7月—2018年6月收治的阿尔茨海默病伴吞咽障碍患者106例,采用随机数表法,分为观察组和对照组,各53例,实施肠内营养支持。对照组给予常规鼻饲方式注入营养液,观察组患者采用连续输注泵法注入肠内营养液。观察两组患者血清白蛋白、血红蛋白、上臂三头肌肌围变化,对比两组患者并发症发生情况。结果治疗后观察组患者的血清白蛋白(serum albumin,ALB)、血红蛋白(hemogIobin,Hb)、上臂三头肌肌围(arm muscle circumference,AMC)(37.89±4.69)g/L、(128.03±9.06)g/L、(23.87±2.03)cm,明显高于对照组的(33.57±4.68)g/L、(114.93±9.05)g/L、(19.42±2.02)cm,差异有统计学意义(t=4.746、7.447、11.312,P<0.05);观察组患者腹胀、呕吐发生率为5.66%、3.77%,明显低于对照组的20.75%和22.64%,差异有统计学意义(χ^(2)=5.267、8.229,P<0.05)。结论对阿尔茨海默病伴吞咽障碍患者实施肠内营养支持能有效改善患者的营养状况,减少并发症的发生,值得临床推广使用。Objective To investigate the effects of two methods of nasal feeding enteral nutrition support on patients with Alzheimer's disease with dysphagia and analysis of complications.Methods A total of 106 patients with Alzheimer's disease and dysphagia admitted from July 2017 to June 2018 were selected and divided into observation group and control group,53 cases in each group,with enteral nutrition support by random number table method.The control group was given conventional nasal feeding to inject the nutrient solution,and the observation group was given the continuous infusion pump method to inject the enteral nutrient solution.The changes in serum albumin,hemoglobin,and upper arm triceps muscle circumference were observed between the two groups of patients,and the complications of the two groups were compared.Results After treatment,the serum albumin(ALB),hemogIobin(Hb),arm muscle circumference(AMC)(37.89±4.69)g/L,(128.03±9.06)g/L,(23.87±2.03)cm of the observation group were significantly higher than those of the control group(33.57±4.68)g/L,(114.93±9.05)g/L,(19.42±2.02)cm,the difference was statistically significant(t=4.746,7.447,11.312,P<0.05);the incidence of abdominal distension and vomiting in the observation group was 5.66%and 3.77%,which were significantly lower than the 20.75%and 22.64%in the control group.The difference was statistically significant(χ^(2)=5.267,8.229,P<0.05).Conclusion Enteral nutrition support for patients with Alzheimer's disease with dysphagia can effectively improve the nutritional status of patients and reduce the occurrence of complications,and it is worthy of clinical application.

关 键 词：阿尔茨海默病 吞咽障碍 肠内营养 并发症 

分 类 号：R4[医药卫生—临床医学]