妊娠晚期孕妇GBS阳性患者与胎膜早破的关联及对母婴预后的影响研究  

Study on the association between GBS positive women and premature rupture of membranes in late pregnancy and its influence on maternal and infant prognosis

作　　者：蔡红丹 CAI Hong-dan(Department of Obstetrics,Dongguan Guangji Hospital,Guangdong Province,Dongguan523690,China)

机构地区：[1]广东省东莞广济医院产科,广东东莞523690

出　　处：《中国当代医药》2021年第18期73-76,共4页China Modern Medicine

基　　金：广东省东莞市社会科技发展(一般)项目(202050715062789)。

摘　　要：目的探讨B族链球菌(GBS)阳性对妊娠晚期胎膜早破孕妇母婴预后的影响。方法选取2018年1月~2020年3月东莞广济医院收治的100例妊娠晚期胎膜早破孕妇作为胎膜早破组,选取同期在东莞广济医院行常规孕检的100例正常妊娠孕妇作为对照组。比较两组的GBS感染阳性率,分析GBS感染阴性与GBS感染阳性胎膜早破孕妇的分娩情况、新生儿情况。结果胎膜早破组的GBS感染阳性率为19.00%,高于对照组的5.00%,差异有统计学意义(P<0.05);GBS感染阴性与GBS感染阳性胎膜早破孕妇的产后出血率比较,差异无统计学意义(P>0.05);GBS感染阳性组的剖宫产、早产、宫内感染、胎儿窘迫、产褥感染占比分别为36.84%、36.84%、21.05%、26.32%、36.84%,高于GBS感染阴性组的9.88%、7.41%、3.70%、3.70%、7.41%,差异有统计学意义(P<0.05);GBS感染阳性组的新生儿窒息、新生儿感染、新生儿肺炎、新生儿黄疸、绒毛膜羊膜炎占比分别为31.58%、26.32%、26.32%、47.37%、21.05%,高于GBS感染阴性组的2.47%、4.94%、0.00%、14.81%、2.47%,差异有统计学意义(P<0.05)。结论妊娠晚期胎盘早破孕妇的GBS感染阳性率较高,GBS感染会增加不良妊娠结局的发生率。Objective To investigate the effect of Group B streptococcus(GBS)positive on maternal and infant prognosis of pregnant women with premature rupture of membranes in late pregnancy.Methods A total of 100 pregnant women with premature rupture of membranes in late pregnancy treated in Dongguan Guangji Hospital from January 2018 to March 2020 were selected as the premature rupture of membranes group.A total of 100 normal pregnant women underwent routine pregnancy examination in Dongguan Guangji Hospital during the same period were selected as control group.The positive rate of GBS infection was compared between the two groups,and the delivery and neonatal conditions of pregnant women with GBS negative and positive GBS infection were analyzed.Results The positive rate of GBS infection in premature rupture of membranes group was 19.00%,higher than 5.00%of control group,the difference was statistically significant(P<0.05).There was no significant difference in postpartum bleeding rate between GBS infection negative and GBS infection positive women(P>0.05).The proportions of cesarean section,premature delivery,intrauterine infection,fetal distress and puerperal infection in GBS infection positive group were 36.84%,36.84%,21.05%,26.32%and 36.84%,respectively,which were higher than those in negative GBS infection group,the differences were statistically significant(P<0.05).The percentages of neonatal asphyxia,neonatal infection,neonatal pneumonia,neonatal jaundice and chorioamnionitis in positive GBS infection group were 31.58%,26.32%,26.32%,47.37%and 21.05%,respectively,which were higher than 2.47%,4.94%,0.00%,14.81%and 2.47%in GBS infection negative group,the differences were statistically significant(P<0.05).Conclusion The incidence of GBS infection in the pregnant women with premature rupture of membranes in late pregnancy is higher,and GBS infection will increase the incidence of adverse pregnancy outcomes.

关 键 词：妊娠晚期孕妇 B族链球菌感染 胎膜早破 母婴预后 

分 类 号：R714.251[医药卫生—妇产科学]