Adaptation to visual stimulation modifies the burst firing property of V1 neurons  

作　　者：Rui-Long LIU Ke WANG Jian-Jun MENG Tian-Miao HUA Zhen LIANG Min-Min XI 

机构地区：[1]College of Life Sciences,Anhui Normal University,Wuhu 241000,China [2]Department of Bio-Medical Engineering,Anhui Medical University,Hefei 230032,China [3]Management School,Queen’s University,UK

出　　处：《Zoological Research》2013年第S03期101-108,共8页动物学研究（英文）

基　　金：This work was supported by the National Natural Science Foundation of China(31171082);the Natural Science Foundation of Anhui Province(070413138);the Key Research Foundation of the Anhui Provincial Education Department(KJ2009A167);the Foundation of Key Laboratories of Anhui Province and the Anhui Provincial Education Department.

摘　　要：The mean firing rate of visual cortical neurons is reduced after prolonged visual stimulation,but the underlying process by which this occurs as well as the biological significance of this phenomenon remains unknown.Computational neuroscience studies indicate that high-frequency bursts in stimulus-driven responses can be transmitted across synapses more reliably than isolated spikes,and thus may carry accurate stimulus-related information.Our research examined whether or not adaptation affects the burst firing property of visual cortical neurons by examining changes in the burst firing changes of V1 neurons during adaptation to the preferred visual stimulus.The results show that adaptation to prolonged visual stimulation significantly decreased burst frequency(bursts/s)and burst length(spikes/burst),but increased burst duration and the interspike interval within bursts.These results suggest that the adaptation of V1 neurons to visual stimulation may result in a decrease of feedforward response gain but an increase of functional activities from lateral and/or feedback connections,which could lead to a reduction in the effectiveness of adapted neurons in transmitting information to its driven neurons.

关 键 词：Visual adaptation Burst firing NEURONS Primary visual cortex CAT 

分 类 号：TP3[自动化与计算机技术—计算机科学与技术]