五味子多糖的分离纯化及其抗糖尿病研究进展  

The Separation and Purification of Schisandra chinensis Polysaccharides and Their Anti-diabetes Research Progress

作　　者：吴伦[1] 高悦 李静 任文晨 苏阳[2] WU Lun;GAO Yue;LI Jing;REN Wen-chen;SU Yang(Research Institute of Traditional Chinese Medicine,Heilongjiang University of Chinese Medicine,Harbin 150040,China;College of Pharmacy,Heilongjiang University of Chinese Medicine,Harbin 150040,China)

机构地区：[1]黑龙江中医药大学中医药研究院,黑龙江哈尔滨150040 [2]黑龙江中医药大学药学院,黑龙江哈尔滨150040

出　　处：《现代中药研究与实践》2021年第3期88-93,共6页Research and Practice on Chinese Medicines

基　　金：黑龙江省自然科学基金优秀青年项目(YQ2019H028);黑龙江省自然科学基金优秀青年项目(YQ2020H030);黑龙江省博士后科研启动金项目(LBH-Q17167);黑龙江省博士后科研启动金项目(LBH-Q19183);黑龙江省普通本科高等学校青年创新人才培养计划项目(UNPYSCT-2016207);哈尔滨市科技创新人才专项资金项目(青年后备人才)项目[2017RAQXJ214(RC2017QN003037)];黑龙江省留学回国人员择优资助项目[2018383(2018QD0011)];黑龙江中医药大学优秀创新人才支持计划学术带头人计划[201877(2018RCD12)]。

摘　　要：五味子多糖成分具有很强的生物活性,研究表明五味子多糖能有效地缓解糖尿病模型胰岛素抵抗,降低血糖,改善糖尿病样作用。通过对五味子多糖成分及抗糖尿病作用进行详细综述,以期为五味子多糖提取、分离纯化、成分分析及抗糖尿病新药研制提供参考。Schisandra chinensis polysaccharides are highly bioactive,and studies have shown that Schisandra chinensis polysaccharides are effective in relieving insulin resistance in diabetes models,lowering blood sugar,and improving diabetes-like effects.In this study,Schisandra chinensis polysaccharides and anti-diabetic effects are reviewed in detail,with a view to providing reference for Schisandra chinensis polysaccharide extraction,separation purification,composition analysis and the development of new anti-diabetes drugs.

关 键 词：五味子 多糖 分离纯化 糖尿病 

分 类 号：R284[医药卫生—中药学]