参附注射液治疗高位脊髓损伤后体位性低血压的疗效观察  

Observation on Clinical Effects of Shenfu Injection in Treating Postural Hypotension after Spinal Cord Injury

作　　者：杨小霞[1] 于慧金 牛见升 邵鸿生[1] 杨恂[1] 王斌雄[1] 刘海[1] 萧玉婷[1] 张艳[1] YANG Xiaoxia;YU Huijin;NIU Jiansheng;SHAO Hongsheng;YANG Xun;WANG Binxiong;LIU Hai;XIAO Yuting;ZHANG Yan(Gansu Province Hospital of Rehabilitation Center,Lanzhou 730000,China)

机构地区：[1]甘肃省康复中心医院,甘肃兰州730000

出　　处：《西部中医药》2021年第6期92-94,共3页Western Journal of Traditional Chinese Medicine

基　　金：甘肃省中医药管理局课题(GZKP-2020-39)。

摘　　要：目的:观察参附注射液治疗高位脊髓损伤后体位性低血压的疗效。方法:选择高位脊髓损伤后体位性低血压患者58例,随机分为对照组和观察组,每组29例。对照组给予电动直立床训练,观察组在对照组基础上给予参附注射液治疗,连续治疗4周。测定两组治疗前后收缩压、电动直立床最大耐受角度和卧位到直立位平均过渡天数。结果:平卧位、坐位及站立位收缩压两组治疗后均明显升高,与同组治疗前比较,差异有统计学意义(P<0.05);且观察组较对照组升高明显,差异有统计学意义(P<0.05)。电动直立床最大耐受角度两组治疗后均明显增加,与同组治疗前比较,差异有统计学意义(P<0.05);且观察组较对照组增加明显,差异有统计学意义(P<0.05);电动直立床最大耐受角度增加值观察组大于对照组,差异有统计学意义(P<0.05)。卧位到直立位平均过渡天数观察组少于对照组,差异有统计学意义(P<0.05)。结论:参附注射液可升高高位脊髓损伤患者的血压,增加电动直立床最大耐受角度,减少患者电动直立床训练直立需要的时间。Objective:To observe clinical effects of Shenfu injection in the treatment of postural hypotension after spinal cord injury(SCI).Methods:All 58 patients suffering postural hypotension after SCI were randomly allocated to the control group and the observation group,29 cases in each group.The control group was given electric upright bed training,and the observation group accepted the infusion of Shenfu injection based on electric upright bed training,for four weeks consecutively.To detect systolic pressure before and after the treatment,compare maximum tolerance angle and average transition days from supine to upright position of electric upright bed in both groups.Results:Systolic pressure in supine,sitting and standing positions rose notably after treating in both groups,it showed significant difference within the same group before and after treating(P<0.05),compared with the control group,systolic pressure in supine,sitting and standing positions rose notably in the observation group,and the difference showed statistical meaning(P<0.05);maximum tolerance angle of electric upright bed after treating increased remarkably,and it had statistical difference within the same group before and after treating(P<0.05).The observation group was superior to the control group in maximum tolerance angle of electric upright bed(P<0.05);the increase of maximum tolerance angle larger than that of the control group,and the difference showed statistical meaning(P<0.05);the average transition days of the observation group were less than those of the control group,and the difference was statistically significant(P<0.05).Conclusion:Shenfu injection could notably lift blood pressure,increase maximum tolerance angle of electric upright bed,reduce time required for electric upright bed training and it could help the patients′recovery.

关 键 词：体位性低血压 脊髓损伤 参附注射液 疗效观察 

分 类 号：R544.2[医药卫生—心血管疾病]