成人突发性聋患者听性脑干反应及40 Hz听觉诱发电位与主观纯音听阈测定结果分析  

Analysis on the correlation of auditory brain/stem response and 40 Hz auditory event related potential by pure tone audiometry in adult patients with sudden deafness

作　　者：何玉娇 杨丽辉[1] HE Yujiao;YANG Lihui(Department of Otolaryngology,Liaoning Provincial People's Hospital,Shenyang,110000,China)

机构地区：[1]辽宁省人民医院耳鼻咽喉科,沈阳110000

出　　处：《临床耳鼻咽喉头颈外科杂志》2021年第6期535-537,542,共4页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

摘　　要：目的:研究听性脑干反应(ABR)及40 Hz听觉诱发电位(40 Hz AERP)在成人突发性聋患者中的价值。方法:治疗前对成人突发性聋患者132例(184耳)进行纯音测听、ABR及40 Hz AERP测试。根据纯音测听听力损失累及的频率和程度,分为低频下降型(86耳)、高频下降型(60耳)、平坦型(32耳)和全聋型(6耳,因ABR及40 Hz AERP反应阈引出不全未做统计),共收集178耳做出统计结果。治疗后再进行纯音测听、ABR及40 Hz AERP测试。结果:治疗前各型听力损失ABR阈值与主观纯音测听500 Hz阈值相关性差(r=0.233,P=0.706),与1000 Hz阈值相关性较差(r=0.472,P=0.345),与2000 Hz阈值相关性较好(r=0.878,P=0.021),与4000 Hz阈值相关性好(r=0.800,P=0.010)。各型听力损失40 Hz AERP阈值与主观纯音测听500 Hz阈值相关性好(r=0.992,P=0),与1000 Hz阈值相关性较好(r=0.912,P=0.110),与2000 Hz阈值相关性较差(r=0.210,P=0.690),与4000 Hz阈值相关性差(r=0.370,P=0.945)。ABR与主观纯音测听在高频相关性高,40 Hz AERP与主观纯音测听在低频相关性高。结论:ABR及40 Hz AERP共同评估,能更全面反映成人突发性聋患者的听力损失程度。Objective:To study the value of auditory brainstem response(ABR)and 40 Hz auditory evoked potential(40 Hz AERP)in adult patients with sudden deafness.Methods:Pure tone audiometry,ABR and 40 Hz AERP were performed in 184 adult patients with sudden deafness before treatment.According to the frequency and severity of hearing loss revealed by pure tone audiometry,the patients were divided into low-frequency decline type(86 cases),high-frequency decline type(60 cases),flat type(32 cases)and total deafness type(6 cases,statistical analysis were not conducted in this group due to the incomplete elicitation of reaction threshold).Data from 178 ears were collected for statistical results.After treatment,pure tone audiometry,ABR and 40 Hz AERP were performed.Results:As for ABR threshold,its correlation with 500 Hz threshold of subjective pure tone test was poor(r=0.233,P=0.706),and was worse with 1000 Hz threshold(r=0.472,P=0.345).ABR threshold was closely correlated with 2000 Hz threshold(r=0.878,P=0.021)and 4000 Hz threshold(r=0.800,P=0.010)of subjective pure tone test.As for 40 Hz AERP threshold,its correlation with 500 Hz threshold of subjective pure tone audiometry was good(r=0.992,P=0),and was better with 1000 Hz threshold(r=0.912,P=0.110).40 Hz AERP threshold was poorly correlated with 2000 Hz threshold(r=0.210,P=0.690)and 4000 Hz threshold(r=0.370,P=0.945)of subjective pure tone audiometry.ABR and subjective pure tone audiometry have high correlation at high frequency,while 40 Hz AERP and subjective pure tone audiometry have high correlation at low frequency.Conclusion:ABR and 40 Hz AERP can comprehensively reflect the severity of hearing loss in adult patients with sudden deafness.

关 键 词：聋 突发性 听性脑干反应 听觉诱发电位 主观纯音听阈测定 

分 类 号：R764.43[医药卫生—耳鼻咽喉科]