脑白质病变与相关血管性认知障碍的MRI研究进展  

MRI research progress of white matter lesions and related vascular cognitive impairment

作　　者：李晓陵[1] 刘晓慧 曹丹娜[1] 王丰[1] 曲冰[1] 姜晓旭 蔡丽娜 姚春丽 崔璇 LI Xiaoling;LIU Xiaohui;CAO Danna;WANG Feng;QU Bing;JIANG Xiaoxu;CAI Lina;YAO Chunli;CUI Xuan(Department of CT and MRI,the First Affiliated Hospital of Heilongjiang University of Chinese Medicine,Harbin 150040,China;Graduate School of Heilongjiang University of Chinese Medicine,Harbin 150040,China)

机构地区：[1]黑龙江中医药大学附属第一医院CT磁共振科,哈尔滨150040 [2]黑龙江中医药大学研究生院,哈尔滨150040

出　　处：《磁共振成像》2021年第7期98-101,共4页Chinese Journal of Magnetic Resonance Imaging

基　　金：国家自然科学基金面上项目(编号:82074537、81973930);黑龙江省自然科学基金项目(编号:LH2020H103,H2016081);哈尔滨市优秀学科带头人项目基金(编号:2016RAXYJ096);黑龙江省中医药科研项目(编号:ZHY2020-100);黑龙江中医药大学研究生创新科研项目(编号:2020yjscx006)。

摘　　要：通过检索脑白质病变(white matter lesion,WML)及血管性认知障碍(vascular cognitive impairment,VCI)相关研究和两者内在关联性的文献,从引起WML的病因、WML导致认知障碍及WML引发VCI可能的内在机制等方面,逐渐深入讨论WML与VCI的内在关联性与中枢机制,为临床预防和治疗提供理论依据。MRI技术以其独特优势在临床认知研究中作用重大,提高VCI的检出率,为其机制研究提供可靠技术手段。By searching the literatures about white matter lesion(WML)and vascular cognitive impairment(VCI)and their internal correlation,the internal correlation and central mechanism of WML and VCI are gradually discussed from the aspects of etiology of WML,cognitive impairment caused by WML and possible internal mechanism of VCI caused by WML,so as to provide theoretical basis for clinical prevention and treatment.MRI technology plays an important role in clinical cognitive research with its unique advantages.It can improve the detection rate of VCI and provide reliable technical means for its mechanism research.

关 键 词：脑白质病变 血管性认知障碍 脑小血管病 胆碱能系统 磁共振成像 

分 类 号：R445.2[医药卫生—影像医学与核医学] R749.1[医药卫生—诊断学]