出 处:《牡丹江医学院学报》2021年第4期96-99,共4页Journal of Mudanjiang Medical University
摘 要:目的探讨内观认知疗法联合复合维生素B、氯硝西泮治疗酒精依赖患者的临床效果。方法回顾性分析焦作市第四人民医院心理科2018年1月至2019年12月间接收的124例酒精依赖患者的临床资料,按干预方案不同分组,将其中以维持药物(复合维生素B、氯硝西泮)替代干预的59例患者列为对照组;在维持药物替代的同时配合实施内观认知疗法干预的65例患者列为研究组。比较两组干预前后酒精依赖症状宾夕法尼亚酒精渴求量表(Pennsylvania Alcohoi Craving Scale,PACS)、脑电生理活动(P3潜伏期、P3波幅)、领悟社会支持程度量表(perceived social support scale,PSSS)、心理状态(Symptom checklist-90,SCL-90)及干预后6个月内的复饮率。结果干预后两组PACS量表各项评分均降低,研究组低于对照组(P<0.05);干预后两组P3潜伏期缩短、P3波幅升高,研究组均优于对照组(P<0.05);干预后研究组PSSS评分高于对照组、SCL-90评分低于对照组(P<0.05);干预后6个月内,研究组复饮率为18.46%(12/65),低于对照组55.93%(33/59),差异均具有统计学意义(P<0.05)。结论内观认知疗法联合复合维生素B、氯硝西泮治疗酒精依赖患者的临床效果显著,可有效减轻患者酒精依赖症状,改善其脑电生理活动,同时提升其领悟社会支持及心理健康状况,降低复饮率。Objective To investigate the clinical effect of Neiguan cognitive therapy combined with vitamin B and clonazepam in the treatment of alcohol dependence.Methods The clinical data of 124 patients with alcohol dependence admitted in our hospital from January 2018 to December 2019 were retrospectively analyzed.According to different intervention schemes,59 patients with maintenance drugs(vitamin B complex and clonazepam)were selected as the control group,and it included 65 patients with implementing insight cognitive therapy intervention while maintaining drug substitution in the study group.The symptoms of alcohol dependence(Pennsylvania Alcohoi Craving Scale,PACS),EEG activity(P3 latency,P3 amplitude),perceived social support(perceived social support scale,PSSs),mental state(Symptom checklist-90,SCL-90 score)and relapse rate within 6 months after intervention were compared between the two groups.Results After the intervention,the scores of PACS in the two groups were decreased,and those in the study group were lower than those in the control group(P<0.05).After the intervention,the P3 latency of the two groups was shortened and the amplitude of P3 was increased,which was better than that of the control group(P<0.05).After the intervention,the PSSs score of the study group was higher than that of the control group,and the SCL-90 score was lower than that of the control group(P<0.05).Within 6 months after the intervention,the rehydration rate of the study group was 18.46%(12/65),lower than that of the control group The control group was 55.93%(33/59)(P<0.05).Conclusion The clinical effect of Neiguan cognitive therapy combined with vitamin B and clonazepam in the treatment of alcohol dependence is significant,which can effectively reduce the symptoms of alcohol dependence,improve their brain electrophysiological activities,and enhance their understanding of social support and mental health,so as to significantly reduce the relapse rate.
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