我国鸡传染性支气管炎病毒的遗传变异和进化分析  

Genetic evolution analysis of infectious bronchitis virus in China

作　　者：李玉杰[1] 盛媛 魏秀丽 徐恩民 吴静[2] 刘娜 马秀丽[2] LI Yujie;SHENG Yuan;WEI Xiuli;XU Enmin;WU Jing;LIU Na;MA Xiuli(Shandong animal disease prevention and control center,Jinan 250102,China;Shandong Institute of Poultry Science,Shandong Academy of Agricultural Science,The Key lab of poultry disease diagnosis and immunology of Shandong Province,Poultry Breeding Engineering Technology Center of Shandong Province,Jinan 250100,China;Shandong Centerfor Quality Control of Feed and Veterinary Drugs,Jinan 250010,China;Shandong Pro vincial Center for Quality and Safety of Animal Products,Jinan 250102,China)

机构地区：[1]山东省动物疫病预防与控制中心,山东济南250102 [2]山东省农业科学院家禽研究所山东省禽病诊断与免疫重点实验室山东省家禽育种工程技术研究中心,山东济南250100 [3]山东省饲料兽药质量检验中心,山东济南250010 [4]山东省畜产品质量安全中心,山东济南250102

出　　处：《家禽科学》2021年第6期5-9,共5页Poultry Science

基　　金：山东省农业重大应用技术创新项目(SD2019XM004);山东省重点研发计划项目(2019GNC106044);山东省现代农业产业技术体系项目(SDAIT-11-01);山东省农业科学院农业科技创新工程(CXGC2021A39)。

摘　　要：本研究测定了2020年以来本实验室从不同地区分离的44个IBV毒株的S1基因序列,并与参考株序列进行比较分析。结果发现分离的44个IBV毒株共占据5个分支。其中:第一分支为QX型,包括25个分离株,QX型分离株又分为ClusterⅠ亚分支(7个)和ClusterⅡ亚分支(18个);第二分支为4/91型,包括12个分离株;第三分支为LDT3型,包括3个分离株;第四分支为Mass型,包括2个分离株;第五分支为TW型,包括2个分离株。从毒株遗传进化分析结果可以看出,QX型仍是我国IBV流行的主要基因型。In this study, the S1 gene sequences of 44 IBV strains isolated from different regions since 2020 were determined and sequenced. The results showed that 44 strains of IBV evolved into five genetic lineages, 25 isolates were distributed into QX lineage. QX lineage isolates were further divided into cluster I subfamily(7 strains) and cluster Ⅱ subfamily(18 strains). 12 isolates were distributed into 4/91 lineage.While LDT3 lineage included three isolates,Mass lineage included two isolates and TW lineage included two isolates. Results of genetic evolution analysis described QX was still the main genotype of IBV in China.

关 键 词：传染性支气管炎病毒 S1基因 遗传变异 进化变异 

分 类 号：S858.31[农业科学—临床兽医学]