多模态磁共振功能成像评估胰腺纤维化程度研究进展  

Research progress of evaluating pancreatic fibrosis degree by multimodal magnetic resonance functional imaging

作　　者：刘畅[1] 石喻[1] LIU Chang;SHI Yu(Department of Radiology,Shengjing Hospital,China Medical University,Shenyang 110004,China)

机构地区：[1]中国医科大学附属盛京医院放射科,沈阳110004

出　　处：《磁共振成像》2021年第6期114-117,共4页Chinese Journal of Magnetic Resonance Imaging

基　　金：国家自然科学基金面上项目(编号:81771802,81771893,82071885)。

摘　　要：胰腺纤维化(pancreatic fibrosis,PF)是多种原因导致胰腺损伤修复的重要组织学改变,PF与慢性胰腺炎(chronic pancreatitis,CP)、胰腺肿瘤等胰腺疾病的发病机制、治疗反应和疾病进展密切相关。早期诊断PF,并及早进行临床干预,对减缓病情、改善患者预后具有重要意义。近年来,以影像学检查为首的无创性检查方法在PF诊断方面发展迅速,其中以磁共振弹性成像、体素内不相干运动扩散加权成像、T1 mapping技术为著,笔者针对PF的多模态磁共振弹性功能成像评估价值作一综述。Pancreatic fibrosis is an important histological change in the repair of pancreatic injury caused by various reasons.Pancreatic fibrosis is closely related to the pathogenesis,therapeutic response and disease progression of pancreatic diseases such as chronic pancreatitis and pancreatic tumor.Early diagnosis of pancreatic fibrosis and early clinical intervention are of great significance for slowing down the disease and improving the prognosis of patients.In recent years,non-invasive examination methods,led by imaging examination,have developed rapidly in the diagnosis of pancreatic fibrosis,with magnetic resonance elastography as the focus.This article reviews the evaluation value of magnetic resonance elastography for pancreatic fibrosis.

关 键 词：胰腺纤维化 磁共振弹性成像 体素内不相干运动 扩散加权成像 磁共振纵向弛豫时间T1技术 磁化转移成像 

分 类 号：R445.2[医药卫生—影像医学与核医学] R576[医药卫生—诊断学]