肺心宁胶囊对AECOPD合并右心衰竭患者BODE指数、CRP及生活质量的影响  

Effects of Feixinning Capsules on BODE Index,CRP and Quality of Life in AECOPD Patients with Right Heart Failure

作　　者：温一琪 张瑞芬 苏和 Wen Yiqi;Zhang Ruifen;Su He(Inner Mongolia Medical University,Inner Mongolia,Hohhot 010010,China)

机构地区：[1]内蒙古医科大学,内蒙古呼和浩特010010 [2]内蒙古自治区中医医院,内蒙古自治区中医药研究所,内蒙古呼和浩特010020

出　　处：《中国中医急症》2021年第7期1185-1188,共4页Journal of Emergency in Traditional Chinese Medicine

基　　金：内蒙古自治区科学技术厅科技成果转化项目(CGZH2018176);内蒙古自治区科学技术厅科技创新引导项目(KCBJ2018043)。

摘　　要：目的观察肺心宁胶囊对慢性阻塞性肺疾病急性加重期(AECOPD)合并右心衰竭(痰热中阻证)患者的疗效。方法将60例AECOPD合并右心衰竭(痰热中阻证)患者随机分为两组各30例。肺心宁组采用肺心宁胶囊联合西医常规治疗,对照组采用西医常规治疗。对两组患者治疗前后肺功能、C反应蛋白(CRP)、CAT评分、BODE指数项目指标、EQ-5D指数进行比较。结果治疗后肺心宁组患者肺功能、CRP、CAT评分、6MWD、mMRC、BODE指数、EQ-5D指数较对照组明显改善(P<0.05),BMI指数变化差异无统计学意义(P>0.05)。结论肺心宁胶囊可有效改善AECOPD合并右心衰竭(痰热中阻证)患者临床症状及生活质量。Objective:To investigate the therapeutic effect of Feixinning Capsules on acute exacerbation of chronic obstructive pulmonary disease(AECOPD)complicated with right heart failure.Methods:A total of 60 cases of AECOPD with right heart failure and phlegm-heat syndrome were randomly selected as the study subjects,and were divided in to the Feixinning group(n=30)and the control group(n=30).The Feixinning group was treated with Feixinning Capsules combined with conventional western medicine,and the control group was treated with conventional western medicine.The pulmonary function,CRP,CAT score,BODE index item index,and EQ-5D index were compared between the two groups before and after treatment.Results:After treatment,the pulmonary function,CRP,CAT score,6 MWD,m MRC,BODE index and EQ-5D index in the Feixinning group were significantly improved compared with the control group(P<0.05),and there was no statistical difference in the change of BMI index(P>0.05).Conclusion:Feixinning Capsules can effectively improve the clinical symptoms and quality of life of patients with AECOPD complicated with right heart failure and phlegm-heat syndrome.

关 键 词：慢性阻塞性肺疾病急性加重期 右心衰竭 痰热中阻证 肺心宁胶囊 BODE指数 EQ-5D指数 

分 类 号：R563.9[医药卫生—呼吸系统] R541.61[医药卫生—内科学]