通窍鼻炎颗粒联合糠酸莫米松治疗小儿腺样体肥大风热蕴肺证的疗效评价  

Efficacy Evaluation of Tongqiao Biyan Granules Combined with Mometasone Furoate on Adenoid Hypertrophy in Children with Syndrome of Wind-Heat Accumulated in Lung

作　　者：周璐[1] 郭旭[1] 孙科佳 ZHOU Lu;GUO Xu;SUN Kejia(Children′s Hospital Affiliated to Zhengzhou University/Henan Children′s Hospital/Zhengzhou Children′s Hospital,Henan Zhengzhou 450002, China)

机构地区：[1]郑州大学附属儿童医院/河南省儿童医院/郑州儿童医院,河南郑州450002

出　　处：《中国医药导刊》2021年第6期433-436,共4页Chinese Journal of Medicinal Guide

摘　　要：目的:观察通窍鼻炎颗粒联合糠酸莫米松治疗小儿腺样体肥大风热蕴肺证的临床疗效。方法:将我院收治的90例腺样体肥大风热蕴肺证患儿随机分为对照组和观察组,各45例,分别给予糠酸莫米松鼻喷雾剂,通窍鼻炎颗粒联合糠酸莫米松鼻喷雾剂,疗程均为30 d。观察两组患儿治疗前后临床症状(鼻阻塞、打鼾、张口呼吸)、血清炎性因子[嗜酸性粒细胞(EOS)、特异性变应原IgE(sIgE)、白三烯C_(4)(LTC_(4))]、免疫指标(IgA、IgG、IgM)、鼻咽侧位片腺样体/鼻咽腔(A/N)值。比较两组患儿疗效及不良反应。结果:观察组总有效率95.5%(42/44),高于对照组的78.6%(33/42)(P<0.05)。观察组患儿的临床症状、血清炎性因子水平、免疫指标、鼻咽侧位片A/N值较对照组改善更为明显,差异有统计学意义(P<0.05)。两组患儿不良反应发生率无统计学差异(P>0.05)。结论:通窍鼻炎颗粒联合糠酸莫米松治疗小儿腺样体肥大风热蕴肺证安全有效。Objective:To evaluate the efficacy of tongqiao biyan granules combined with mometasone furoate on adenoid hypertrophy in children with syndrome of wind-heat accumulated in lung.Methods:90 cases adenoid hypertrophy children with syndrome of wind-heat accumulated in lung were randomly divided into the control group and the observation group,45 cases in each group.Mometasone furoate nasal spray,tongqiao biyan granules combined with mometasone furoate nasal spray were given respectively for 30 days.Clinical symptoms(nasal obstruction,snoring,open-mouth breathing)and serum inflammatory factors(EOS,sIgE,LTC_(4)),immunoglobulin(IgA,IgG,IgM),lateral nasopharyngeal radiograph A/N indicators were observed in the two groups of patients before and after treatment,and the efficacy and adverse reactions of the two groups were compared.Results:The total effective rate of the observation group was 95.5%(42/44),which was higher than that of the control group(78.6%,33/42)(P<0.05).The clinical symptoms,inflammatory factors level,immunoglobulin level,lateral nasopharyngeal radiograph A/N indicators in the observation group were improved more significantly than the control group(P<0.05).The adverse effects rate of the two groups had no statistical difference(P>0.05).Conclusion:Tongqiao biyan granules combined with mometasone furoate is safe and effective in treating adenoid hypertrophy in children with syndrome of wind-heat accumulated in lung.

关 键 词：通窍鼻炎颗粒 糠酸莫米松 腺样体肥大 风热蕴肺证 

分 类 号：R729[医药卫生—儿科]