慢性阻塞性肺疾病患者慢性牙周炎与肺功能相关性  

Correlation between Chronic Periodontitis and Lung Function in Patients with Chronic Obstructive Pulmonary Disease

作　　者：许云海[1] 安欣 杨婷[1] 郭涛[1] 许音[1] 赵晓军[3] XU Yun-hai;AN Xin;YANG Ting;GUO Tao;XU Yin;ZHAO Xiao-jun(Department of Stomatology,Hebei Chest Hospital,Shijiazhuang 050041,China;Department of Humanitarian Nursing,Hebei University of Traditional Chinese Medicine,Shijiazhuang 050200,China;Department of Stomatology,the Second Hospital of Shijiazhuang City,Shijiazhuang 050000,China)

机构地区：[1]河北省胸科医院口腔科,石家庄050041 [2]河北中医学院人文护理教研室,石家庄050200 [3]石家庄市第二医院口腔科,石家庄050000

出　　处：《临床误诊误治》2021年第7期55-59,共5页Clinical Misdiagnosis & Mistherapy

基　　金：河北省财政厅老年病防治项目(361013)。

摘　　要：目的探讨慢性阻塞性肺疾病(COPD)患者慢性牙周炎与肺功能相关性。方法将2019年6月-2020年10月在社区招募的COPD 232例作为COPD组,健康人268例作为健康组。比较两组一般资料和牙周检查结果,并对COPD患者行肺功能检测,分析COPD患者慢性牙周炎与肺功能相关性。结果两组性别和年龄等一般资料比较差异无统计学意义(P>0.05)。COPD组慢性牙周炎患病率高于健康组,牙周探诊深度深于健康组,附着丧失水平和菌斑指数高于健康组,缺牙数多于健康组,差异有统计学意义(P<0.05或P<0.01)。COPD患者随着慢性牙周炎程度逐渐加重,第1秒用力呼气容积占用力肺活量百分比(FEV1/FVC)和第1秒用力呼气容积占预计值百分比(FEV1%)逐渐降低,其中FEV1/FVC和FEV1%慢性牙周炎轻度与中度、重度比较差异均有统计学意义(P<0.01)。Spearman相关性分析结果显示,COPD患者慢性牙周炎程度与FEV1/FVC和FEV1%均呈负相关(P<0.01)。COPD患者不同COPD全球倡仪分级慢性牙周炎患病情况比较差异有统计学意义(P<0.01)。结论COPD患者慢性牙周炎患病率高于健康人群,且慢性牙周炎程度影响肺功能。Objective To explore correlation between chronic periodontitis and lung function in patients with chronic obstructive pulmonary disease(COPD).Methods A total of 232 patients with COPD were recruited in the community between June 2019 to October 2020 as COPD group,while other 268 healthy people at the same period were recruited as healthy group.General information and results of periodontal examination were compared between two groups,and lung function tests were performed for COPD patients to analyze the correlation between chronic periodontitis and lung function of COPD patients.Results There were no statistically significant differences in general informations such as sex and age between two groups(P>0.05).In COPD group,prevalence rate of chronic periodontitis was higher than that in healthy group;probing depth of periodontium was deeper than that in healthy group;level of clinical attachment loss and plaque index were higher than those in healthy group;number of missing teeth was larger than those in healthy group,and the differences were statistically significant(P<0.05 or P<0.01).With gradually aggravating degree of chronic periodontitis,the ratio of forced expiratory volume in one second to forced vital capacity(FEV1/FVC)and percentage of FEV1 to predicted value(FEV1%)were decreased gradually in COPD patients.There were statistically significant differences among patients with mild,moderate and severe chronic periodontitis with regard to FEV1/FVC and FEV1%values(P<0.01).Results of Spearman correlation analysis showed that the severity of chronic periodontitis were negatively correlated with FEV1/FVC and FEV1%(P<0.01).There were statistically significant differences in prevalence conditions of chronic periodontitis of COPD patients with different grades of Global Initiative for Chronic Obstructive Lung Disease(GOLD)(P<0.01).Conclusion The prevalence rate of chronic periodontitis in COPD patients is higher than that in healthy people,and the degree of chronic periodontitis affects lung function.

关 键 词：肺疾病 慢性阻塞性 慢性牙周炎 第1秒用力呼气容积占用力肺活量百分比 第1秒用力呼气容积占预计值百分比 牙周指数 

分 类 号：R563.9[医药卫生—呼吸系统] R781.4[医药卫生—内科学]