青年肺结核复治的人口统计学特征及影响因素分析  

Analysis of population characteristics and infecting factors in youth retreated patients with pulmonary tuberculosis

作　　者：章鑫丽 李晔 ZHANG Xin-li;LI Ye(the 1st Department of Tuberculosis,Anhui Chest Hospital,Hefei,Anhui 230022,China)

机构地区：[1]安徽省胸科医院结核一科,安徽合肥230022

出　　处：《临床肺科杂志》2021年第8期1139-1142,共4页Journal of Clinical Pulmonary Medicine

基　　金：国家科技重大专项项目(No.2018ZX10722302-001-006)。

摘　　要：目的了解青年肺结核复治患者的人口统计学特征以及复治的影响因素。方法回顾性分析2017年1月~2018年12月在安徽省胸科医院确诊的青年肺结核患者的病例资料,统计分析患者的一般情况、人口特征及相关影响因素,并对影响因素进行归纳总结。结果共有408例青年肺结核患者纳入统计分析,复治46例,复治率为11.27%。青年肺结核复治患者中职业不固定、居住地在农村、未婚、收入水平低和文化水平专科以下的居多。有咳嗽咳痰、发热、胸痛胸闷、咯血痰血、盗汗、乏力、体重下降和纳差等临床表现,与普通肺结核无明显区别。职业不固定、居住地在农村、病原学阳性、有肺外结核和重症肺结核的青年肺结核患者更容易转成复治。多因素logistic结果显示病原学阳性(OR=1.986,95%CI:1.043~3.780)、有肺外结核(OR=2.161,95%CI:1.110~4.206)和重症肺结核(2.306,95%CI:1.192~4.461)是青年复治肺结核患者的独立危险因素。结论职业不固定、居住地在农村、病原学阳性、有肺外结核和重症肺结核均是青年肺结核患者复治的影响因素,应重视对该部分高危人群的防治。Objective To explore population characteristics and infecting factors in youth retreated patients with pulmonary tuberculosis in our hospital.Methods The clinical data of young patients who diagnosed with pulmonary tuberculosis in Anhui Chest Hospital from January 2017 to December 2018 were retrospectively analyzed.The general conditions,demographic characteristics and related influencing factors were statistically summarized.Results A total of 408 young pulmonary tuberculosis patients were included in this study,46 cases were retreated,and the re-treatment rate was 11.27%.The majority of young pulmonary tuberculosis retreated patients had irregular occupations,living in rural areas,unmarried,low-income,and low education.Young patients with retreated tuberculosis had clinical manifestations such as cough and sputum,fever,chest pain and distress,hemoptysis,night sweats,fatigue,weight loss,and poor appetite,which were not significantly different from ordinary tuberculosis.Young pulmonary tuberculosis patients with irregular occupations,living in rural areas,positive pathogens,extrapulmonary tuberculosis and severe tuberculosis were more likely to need re-treatment.Multivariate logistic results showed that positive pathogens,extrapulmonary tuberculosis and severe tuberculosis were independent risk factors for the re-treatment of young tuberculosis patients.Conclusion Irregular occupations,living in rural areas,positive pathogens,extrapulmonary tuberculosis and severe tuberculosis are the influencing factors for re-treatment of young tuberculosis patients.We should pay attention to the prevention and treatment of these high-risk groups.

关 键 词：青年肺结核 复治 人口学特征 危险因素 

分 类 号：R521[医药卫生—内科学] R181.3[医药卫生—临床医学]