新型冠状病毒核酸与抗体的检测方法分析  

Analysis of New Coronavirus nucleic acid and antibody detection methods

作　　者：赖姝彧 刘芳[1,2] 常莉[1,2] 车光璐[1,2] 杨秋霞(综述) 刘婷(审校) LAI Shuyu;LIU Fang;CHANG Li;CHE Guanglu;YANG Qiuxia;LIU Ting(Department of Laboratory,West China Second Hospital,Sichuan University,Chengdu,Sichuan 610000,China;Key Laboratory of Birth Defects and Related Maternal and Child Diseases,Ministry of education,Chengdu,Sichuan 610000,China)

机构地区：[1]四川大学华西第二医院检验科,四川成都610000 [2]出生缺陷与相关妇儿疾病教育部重点实验室,四川成都610000

出　　处：《国际检验医学杂志》2021年第S01期197-200,共4页International Journal of Laboratory Medicine

摘　　要：新型冠状病毒肺炎(COVID-19)是由新型冠状病毒(SARS-CoV-2)感染所导致的肺炎,其传播途径主要包括直接传播、气溶胶传播和接触传播。多数COVID-19患者预后良好,少数患者病情危重,甚至死亡。由于该病短期内即在全球范围蔓延,严重危及人类生命健康,因此尽早诊断SARS-CoV-2感染者并采取有效隔离措施,将有助于COVID-19的疾病防控。本文总结了目前国内检验科对SARS-CoV-2核酸和血清特异性抗体的常见检测手段,从检测方法、常见问题等方面进行了分析,旨在推动SARS-CoV-2核酸与抗体联合检测,并尽量规避假阴性、假阳性结果的发生,从而为临床确诊SARS-CoV-2感染者提供有力依据。New Coronavirus pneumonia(COVID-19)is caused by the infection of New Coronavirus(SARS-CoV-2).The main routes of transmission include direct transmission,aerosol transmission and contact transmission.The prognosis of most patients with cowid-19 is good,and a few patients are critically ill or even die.As the disease spreads around the world in a short time and seriously endangers human life and health,early diagnosis of sars-cov-2 infected persons and effective isolation measures will contribute to the prevention and control of the disease.This paper summarized the common detection methods of sars-cov-2 nucleic acid and serum specific antibody in domestic laboratory,analyzed the detection methods and common problems,in order to promote the joint detection of sars-cov-2 nucleic acid and antibody,and try to avoid the occurrence of false negative and false positive results,so as to provide a strong basis for the clinical diagnosis of sars-cov-2 infection.

关 键 词：新型冠状病毒肺炎 新型冠状病毒 核酸检测 抗体检测 

分 类 号：S85[农业科学—兽医学]