早期宫颈癌保留生育能力的手术治疗进展  

Advances in the fertility preserving surgical treatment of early cervical cancer

作　　者：胡水平 贾泽南 张亚男 党云[3] 刘志杰 HU Shuiping;JIA Zenan;ZHANG Yanan;DANG Yun;LIU Zhijie(Gansu University of Traditional Chinese Medicine,Lanzhou 730000,China;The 940th Hospital of Joint Logistic Support Force of PLA;Gansu Provincial Maternal and Child Care Hospital)

机构地区：[1]甘肃中医药大学,甘肃兰州730000 [2]解放军联勤保障部队第940医院 [3]甘肃省妇幼保健院

出　　处：《西北国防医学杂志》2021年第5期418-422,F0003,共6页Medical Journal of National Defending Forces in Northwest China

基　　金：兰州市科技局科技发展指导性计划项目(2017-ZD-36)。

摘　　要：在早期宫颈癌年轻患者的治疗中,保留生育能力的手术(如宫颈锥切术、单纯子宫颈切除术及根治性子宫颈切除术)已被作为根治性子宫切除术的替代方法之一。本研究对早期宫颈癌年轻患者实施保留生育的手术治疗进行综述,发现在合理选择组织病理学参数后,非根治性子宫颈切除术与根治性子宫颈切除术相比,妊娠率更高,妊娠结局更好。在根治性子宫颈切除术中,手术入路的选择似乎在肿瘤及产科结局方面并无较大差异,保留生育能力的手术可以在不影响肿瘤安全性和生殖潜力的情况下获得与根治性子宫切除术同等的术后生存率。In the treatment of young patients with early cervical cancer,fertility preserving surgery(eg.conization of cervix,simple cervicectomy and radical cervicectomy)has been used as an alternative to radical hysterectomy.This paper reviews on tumor and obstetric results of young patients with early cervical cancer after fertility preservation surgery and finds that through proper selection of histopathological parameters,cervical coning and simple cervical resection were associated with higher pregnancy rates and better pregnancy outcomes than radical cervical resection.In radical cervical resection,the choice of surgical approach does not seem to make a significant difference in tumor and obstetric outcomes.Fertility preserving surgery can achieve postoperative survival rates comparable to radical hysterectomy without compromising tumor safety or reproductive potential.

关 键 词：早期宫颈癌 保留生育能力 子宫颈切除术 手术方式 

分 类 号：R711.74[医药卫生—妇产科学]