基于IDEAL-IQ评估感兴趣区大小在胰腺脂肪定量研究中的影响  

The effect of region of interest size in quantitative evaluation of pancreatic fat using IDEAL-IQ

作　　者：杨硕 姚文君[1] 郑穗生[1] YANG Shuo;YAO Wenjun;ZHENG Suisheng(Department of Radiology,the Afiliated Second Hospital of Anhui Medical University,Hefei 230000,China;Department of Radiology,the Afiliated Psychological Hospital of Anhui Medical University,Hefei 230601,China)

机构地区：[1]安徽医科大学第二附属医院放射科,安徽合肥230000 [2]安徽医科大学附属心理医院放射科,安徽合肥230601

出　　处：《实用放射学杂志》2021年第7期1183-1187,1191,共6页Journal of Practical Radiology

基　　金：安徽医科大学校科研基金项目(2020xkj063).

摘　　要：目的 探讨不同大小的感兴趣区(ROI)在IDEAL-IQ定量胰腺脂肪含量时的重复性.方法 纳入80例志愿者行上腹部IDEAL-IQ扫描,由2位医师独立对胰头、胰体及胰尾分别进行3次不同ROI面积下(70~90 mm^(2)、120~140 mm^(2)、170~190 mm^(2))的测量;第1次测量结束后2周,在不参照之前测量结果的情况下再测量1次.采用方差分析两两比较同一测量者在同一部位、不同ROI面积下测量得出的质子密度脂肪分数(PDFF)值的差异性;使用组内相关系数(ICC)评价同一观察者间隔2周,在相同部位、相同ROI面积下测量得出的PDFF值的重复性;使用Bland-Altman方法评价2位观察者在相同部位、相同ROI面积下测量的PDFF值的一致性.结果 2位医师各自测量胰体、胰尾时,将ROI面积为120~140 mm^(2)与170~190 mm^(2)、70~90 mm^(2)与170~190 mm^(2)下测得的PDFF值差异有统计学意义(P<0.05).2位测量者间隔2周,在相同部位、相同ROI面积下的ICC较高.2位观察者在ROI面积为70~90 mm^(2)、120~140 mm^(2)时测量胰腺及170~190 mm^(2)时测量胰头时一致性较好.结论 不同ROI的大小影响IDEAL-IQ对胰腺脂肪定量的结果,ROI面积为70~90 mm^(2)和120~140 mm^(2)时,可重复性较好.Objective To evaluate the repeatability of region of interest(ROI)of different sizes in quantifying pancreatic fat content by IDEAL IQ.Methods A total of 80 volunteers were recruited for the IDEAL IQ scan of the upper abdomen.Two radiologists independently measured the pancreas head,pancreas body and pancreas tail three times under different ROI areas(70-90 mm^(2),120-140 mm^(2),170-190 mm^(2)).Two weeks after the first measurement,it was conducted again without referring to the previous measurement re.sults.The variance analysis was used to compare the differences of proton density fat fraction(PDFF)values measured by the same observers in the same location and different ROI areas.The intra-class correlation coefficient(ICC)was used to evaluate the repeatability of PDFF values measured at the same site and ROI area by the same observer between the two weeks.Blancl-Altman plot was used to evaluate the consistency of PDFF values measured by two observers at the same site and the same ROI area.Results When the two radiologists measured the pancreas body and pancreatic tail separately,the difference of the PDFF values measured under the ROI area of 120-140 mrrr and 170-190 mm^(2),70-90 mmL and 170-190 mm^(2) was statistically significant(P<0.05).ICC was higher at the same location and the same ROI area for two weeks apart.The two observers had good consistency in measuring the pancreas when the ROI was 70-90 mm^(2),120-140 mm^(2) and the head of the pancreas when the ROI was 170-190 mm^(2).Conclusion Different ROI sizes affect the results of IDEAL-IQ in pancreatic fat quantification.When the ROI areas are from 70 mm^(2) to 90 mm^(2) or from 120 mm^(2) to 140 mm^(2),the repeatability is good.

关 键 词：胰腺 感兴趣区 磁共振成像 质子密度脂肪分数 

分 类 号：R322.491[医药卫生—人体解剖和组织胚胎学] R445.2[医药卫生—基础医学]