Gut microbiota signatures in Schistosoma japonicum infection-induced liver cirrhosis patients: a case-control study  

作　　者：Qi-Feng Gui Hui-Lin Jin Feng Zhu Hai-Feng Lu Qin Zhang Jia Xu Yun-Mei Yang Chi Xiao 

机构地区：[1]Department of Geriatrics,The First Affiliated Hospital,School of Medicine,Zhejiang University,Hangzhou,Zhejiang,People's Republic of China [2]不详 [3]School of Basic Medical Sciences&Forensic Medicine,Hangzhou Medical College,Hangzhou,Zhejiang,People's Republic of China

出　　处：《Infectious Diseases of Poverty》2021年第2期83-83,共1页贫困所致传染病（英文）

摘　　要：Background:Several studies have assessed the role of gut microbiota in various cirrhosis etiologies,however,none has done so in the context of Schistosoma joponicum infection in humans.We,therefore,sought to determine whether gut microbiota is associated with S.japonicum infection-induced liver cirrhosis.Methods:From December 2017 to November 2019,24 patients with S.joponicum infection-induced liver cirrhosis,as well as 25 age-and sex-matched controls from the Zhejiang Province,China,were enrolled.Fecal samples were collected and used for 16S rRNA gene sequencing(particularly,the hypervariable V4 region)using the lllumina MiSeq system.Wilcoxon Rank-Sum and PERMANOVA tests were used for analysis.

关 键 词：Gut microbiota 16S rRNA Schistosoma joponicum 

分 类 号：R532.21[医药卫生—内科学]