黄芩苷治疗脂肪性肝病药理作用的研究进 展  

Research Progress of Pharmacological Effects of Baicalin on Fatty Liver Disease

作　　者：程似锦[1] 张程亮 CHENG Sijin;ZHANG Chengliang(Changjiang Polytechnic College,Wuhan 430074,China;Department of Pharmacy,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China)

机构地区：[1]长江职业学院,武汉430074 [2]华中科技大学同济医学院附属同济医院药学部,武汉430030

出　　处：《医药导报》2021年第8期1076-1080,共5页Herald of Medicine

基　　金：国家自然科学基金资助项目(82073939)。

摘　　要：近年来,黄芩苷治疗或缓解肝脏疾病方面的研究逐渐增加。临床上,黄芩苷的有关制剂已经广泛用于急、慢性肝炎、迁延性肝炎的辅助治疗。基于黄芩苷治疗肝脏脂肪病变的机制研究,目前已经获得一定的进展,该文主要从黄芩苷调节脂质作用、抗氧化作用、调节胰岛素水平和功能、升高血管生成素样蛋白6及抗炎作用等几方面,对黄芩苷治疗脂肪性肝病的药理作用研究进展进行综述。In recent years,there are lots of studies on baicalin in liver diseases.Baicalin was used to adjuvant treatment of acute hepatitis,chronic hepatitis and persistent hepatitis.This review will focus on the pharmacological effects of baicalin on fatty liver disease,such as anti-oxidant effects,inhibiting lipogenesis,improve insulin resistance,upregulate angiopotietin like proteins 6 and anti-inflammation effect,etc.

关 键 词：黄芩苷 脂肪性肝病 胰岛素耐受 血管生成素样蛋白6 

分 类 号：R975[医药卫生—药品] R575.5[医药卫生—药学]