GABAergic interneurons mediate inhibitory signal from A-fiber to nocicetive C-fiber  

作　　者：Yu Ning Cui Huan Fang Yehong Liu Fan Wang Tao Yuan Bo Ma Chao 

机构地区：[1]Department of Human Anatomy,Histology and Embryology,Institute of Basic Medical Sciences Chinese Academy of Medical Sciences,Beijing 100005,China

出　　处：《解剖学杂志》2021年第S01期87-87,共1页Chinese Journal of Anatomy

摘　　要：We investigate the morphological and electrophysiological mechanism of gate control for pain.We proposed that the regulation of peripheral A-fibers on C fibers was mediated by the GABAergic interneurons in the spinal cord.The cobra venom was injected to the sciatic nerve to establish a neuropathic pain model due to peripheral demyelination within A-fiber.The content of r aminobutyric acid(GABA)in spinal cord and cerebrospinal fluid was asssed by high performance liquid chromatography(HPLC).The microstructure of A-fiber,C-fiber and the GABAergic neurons in the spinal cord was observed by immunofluorescence staining.

关 键 词：PAIN FIBER fibers 

分 类 号：R28[医药卫生—中药学]