Effect of high flow shear stress on smooth muscle of collateral vessels wall in aged rats hindlimb  

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作  者:Dong Liping Yuan Heng Li Shuangrong Long Juan Liu Guanlan 

机构地区:[1]Department of Histology and Embryology,Academician Work Station,Chang sha Medical University,Changsha 410219,China

出  处:《解剖学杂志》2021年第S01期170-170,共1页Chinese Journal of Anatomy

摘  要:To investigate the effects of high flow shear stress on the smooth muscle of the collateral vessels of hind limbs in aged rats using a collateral vessel growth model of femoral artery ligation plus femoral arter iovenous anastomosis and femoral artery ligation alone.10 adult rats and 15 old rats were divided into adult sham group,adult femoral artery ligation group,aged sham group,aged femoral artery ligation group and aged femoral artery liga tion with femoral arteriovenous shunt group.F emoral artery ligation group was performed with two knots.F emoral art eriovenous shunt group was created a sideto-side anastomosis between the distal stump of the occluded femoral artery and the accompanying vein,The rats survived for 1 week after surgery,collateral vessel growth was examined by imm unofluorescence.

关 键 词:COLLATERAL RATS FEMORAL 

分 类 号:R68[医药卫生—骨科学]

 

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