三种清热解毒类中成药的荧光指纹图谱研究  

Study on the fluorescence fingerprints of three kinds of Chinese patent medicines for Qingre Jiedu

作　　者：朱丹丹 毛越 杨莉丽[1] ZHU Dan-dan;MAO Yue;YANG Li-li(College of Chemistry and Materials Science, Hebei Normal University, Shijiazhuang Hebei 050024,China)

机构地区：[1]河北师范大学化学与材料科学学院,河北石家庄050024

出　　处：《河北省科学院学报》2021年第3期43-47,共5页Journal of The Hebei Academy of Sciences

摘　　要：对4个厂家生产的金莲花胶囊、清火片和复方穿心莲片的三维荧光图谱进行了测定,采用聚类分析法分别对三种中成药的三维荧光图谱的一致性进行考察。在相关系数分别为0.988,0.999和0.981时,4个厂家生产的21个批号63个金莲花胶囊、28个批号84个清火片和47个批号141个复方穿心莲片样本的三维荧光图谱各自聚为一类,结果表明不同厂家生产的金莲花胶囊、清火片和复方穿心莲片的三维荧光图谱分别具有良好的一致性,采用平均值法分别建立了金莲花胶囊、清火片和复方穿心莲片的三维荧光指纹图谱。Three-dimensional(3D)fluorescence spectra of Jinlianhua Jiaonang,Qinghuo Pian and Fufang Chuanxinlian Pian were determined in this paper.The consistency of fluorescence spectra of 3 kinds of Chinese patent medicines was investigated by cluster analysis method,respectively.The 63 Jinlianhua Jiaonang samples of 21 batchs,84 Qinghuo Pian samples of 28 batchs and 141 Fufang Chuanxinlian Pian samples of 47 batchs from four manufacturers were grouped together with the correlation coefficient of 0.988,0.999 and 0.981,respectively.The results showed that 3D fluorescence spectra of Jinlianhua Jiaonang,Qinghuo Pian and Fufang Chuanxinlian Pian produced by different manufacturers had good consistency,respectively.The 3D fluorescence fingerprints of Jinlianhua Jiaonang,Qinghuo Pian and Fufang Chuanxinlian Pian were established by means of the average method.

关 键 词：金莲花胶囊 清火片 复方穿心莲片 中成药 聚类分析 指纹图谱 

分 类 号：R284[医药卫生—中药学]