甘氨酸法制备除草剂草甘膦的酸解工艺优化  

Optimization of Acidolysis Process in the Synthesis of Glyphosate Induced by Glycine Method

作　　者：韩晓丹[1] 王慧宾[1] 付建平[1] 胡居吾[1] Han Xiaodan;Wang Huibin;Fu Jianping;Hu Juwu(Department of Applied Chemistry,Jiang Xi Academic of Sciences,Nanchang,Jiangxi 330096,China)

机构地区：[1]江西省科学院应用化学研究所,江西南昌330096

出　　处：《化学世界》2021年第7期434-438,共5页Chemical World

基　　金：国家自然科学基金(No.21862007);江西省重点研发(Nos.20181BBG70041,20192BBG70060);江西省杰出青年人才(No.20192BCB23027);江西省专利产业化(No.20171BEM26015)资助项目。

摘　　要：以环境友好的非均相活性炭负载对甲苯磺酸(p-TSA/AC)替代传统液体盐酸催化草甘膦生产过程中的酸解反应,考察了p-TSA/AC催化剂的种类和用量、反应时间、反应温度以及催化剂稳定性等因素对草甘膦产率的影响。结果表明,p-TSA/AC催化剂对草甘膦生产工艺中的酸解反应具有良好的催化活性,当催化剂p-TSA/AC-1用量为10 g,反应温度50℃,反应时间3 h,草甘膦的产率为87%,催化剂重复使用5次仍可保持较高活性,该研究为草甘膦酸解反应提供了一种清洁、高效的方法。The acidolysis reaction for the preparation of glyphosate catalyzed by environmentally benign active carbon supported p-toluenesulfonic acid(p-TSA/AC) instead of traditional liquid hydrochloric acid was studied. The effects of acidolysis reaction conditions, such as the type and amount of p-TSA/AC catalyst, reaction time, reaction temperature and catalyst stability, on the synthesis of glyphosate were carefully investigated. The results showed that p-TSA/AC supported on camellia oleifera shell activated carbon had a good catalytic performance for the acidolysis reaction. Under the conditions of m(p-TSA/AC-1)=10 g, acidolysis temperature=50 ℃, and acidolysis time=3 h, the final yield of glyphosate was 87%. After recycled 5 times, the catalytic activity of p-TSA/AC-1 decreased slightly. This study can provide a clean and efficient method for glyphosate acidolysis reaction.

关 键 词：草甘膦 酸解反应 活性炭负载对甲苯磺酸 工艺优化 

分 类 号：O69[理学—化学]