2,7-二甲基-2,4,6-辛三烯-1,8-二醛的合成工艺改进  

The Improvement of Synthetic Process of 2,7-dimethyl-2,4,6-octadiene-1,8-dial

作　　者：项学兵[1] 孔望欣 翟德伟[1] 王平 霍鸿飞 张韩斌 Xiang Xuebing;Kong Wangxin;Zhai Dewei;Wang Ping;Huo Hongfei;Zhang Hanbin(Xinchang Pharmaceutical Factory of Zhejiang Pharmaceutical Co.,Ltd.,Zhejiang,312500;Changhai Biological Branch of Zhejiang Pharmaceutical Co.,Ltd.,Zhejiang,312500)

机构地区：[1]浙江医药股份有限公司新昌制药厂,浙江312500 [2]浙江医药股份有限公司昌海生物分公司,浙江312500

出　　处：《当代化工研究》2021年第14期134-136,共3页Modern Chemical Research

摘　　要：2,7-二甲基-2,4,6-辛三烯-1,8-二醛是合成类胡萝卜素类化合物的重要中间体,工艺以2,5-二甲氧基二氢呋喃和乙氧基-1-丙烯为原料,进行醚化、缩合、碱化和酸化步骤得到合成产物。我们经过工艺改进,实验结果能够大幅提高产品收率,降低产品成本,减小污染等目的。2,7-dimethyl-2,4,6-octadiene-1,8-dial is an important intermediate in the synthesis of carotenoid series compounds.The synthesis product is obtained by etherification,condensation,alkalinization and acidification steps using 2,5-dimethoxydihydrofuran and ethoxy 1-propylene as raw materials.After the process improvement,the experimental results can greatly improve product yield,reduce product cost,reduce pollution and other purposes.

关 键 词：2 7-二甲基-2 4 6-辛三烯-1 8-二醛 缩合 类胡萝卜素 

分 类 号：TQ[化学工程]