自拟化纤通络方辅助治疗特发性肺纤维化的疗效及对运动呼吸的影响  

Self-made Huaxian Tongluo Recipe as an Adjuvant Treatment of Idiopathic Pulmonary Fibrosis and Its Effect on Exercise Breathing

作　　者：朴祥宇 乔世举[2] PIAO Xiangyu;QIAO Shiju(Graduate School of Liaoning University of Traditional Chinese Medicine,Shenyang,Liaoning Province,110000 China;Department of Respiratory Medicine,Second Affiliated Hospital of Liaoning University of Traditional Chinese Medicine,Shenyang,Liaoning Province,110000 China)

机构地区：[1]辽宁中医药大学研究生学院,辽宁沈阳110000 [2]辽宁中医药大学附属第二医院呼吸内科,辽宁沈阳110000

出　　处：《中外医疗》2021年第16期30-33,共4页China & Foreign Medical Treatment

摘　　要：目的探讨自拟化纤通络方辅助治疗特发性肺纤维化的疗效及对运动呼吸的影响。方法便利选择2018年8月—2020年8月经辽宁中医药大学附属第二医院收治的IPF患者60例展开研究,遵照随机数字表法,设置对照组及观察组,对照组行常规西医对症治疗,观察组则辅以自拟化纤通络方联合治疗,治疗持续1疗程,比较两组中医症候积分、运动呼吸情况、肺功能指标。结果经治疗后,两组舌苔、脉象、咳嗽及气喘评分均见不同程度下降,观察组较对照组更低[(1.02±0.11)分vs(2.36±0.74)分、(1.12±0.23)分vs(2.74±1.26)分、(1.15±0.43)分vs(2.66±1.32)分、(2.09±1.08)分vs(3.38±1.21)分],差异有统计学意义(t=9.810、6.928、5.957、4.356,P<0.001);两组6MWD均上升,Borg评分均下降,观察组6MWD高于对照组[(499.12±72.46)m VS(457.19±64.68)m],Borg评分低于观察组[(3.98±0.31)分VS(5.14±0.46)分],差异有统计学意义(P<0.001);两组FEV1、FVC、DLCO指标均见一定提升,观察组均高于对照组[(74.19±4.53)%vs(64.91±4.78)%、(72.39±4.63)%vs(63.24±4.86)%、(60.34±14.51)%vs(49.12±11.28)%],差异有统计学意义(t=7.718、7.466、3.344,P<0.05)。结论IPF患者予以自拟化纤通络方辅助治疗,症候改善,运动呼吸情况良好,肺功能增强。Objective To explore the effect of self-made Huaxian Tongluo Recipe in the auxiliary treatment of idiopathic pulmonary fibrosis and its influence on exercise breathing.Methods Sixty cases of IPF patients admitted to the Second Affiliated Hospital of Liaoning University of Traditional Chinese Medicine from August 2018 to August 2020 were convenient selected for this study.According to the random number table method,a control group and an observation group were set up.The control group received conventional western medicine symptomatic treatment,while the observation group was supplemented with self-designed chemical fiber tongluo prescription combined treatment for 1 course of treatment.The scores of TCM symptoms,exercise respiration and lung function were compared between the two groups.Results After treatment,the tongue coating,pulse,cough and asthma scores of the two groups were decreased to varying degrees.The observation group was lower than the control group[(1.02±0.11)points vs(2.36±0.74)points,(1.12±0.23)points vs(2.74±1.26)points,(1.15±0.43)points vs(2.66±1.32)points,(2.09±1.08)points vs(3.38±1.21)],the difference was statistically significant(t=9.810,6.928,5.957,4.356,P<0.001);6MWD increased and Borg score decreased in both groups.6MWD in the observation group was higher than that in the control group[(499.12±72.46)m VS(457.19±64.68)m].Borg score was lower than that in the untrol group[(3.98±0.31)points vs(5.14±0.46)points],the difference was statistically significant(P<0.001);The FEV1,FVC and DLCO indexes of both groups were improved to some extent.The observation group was higher than the control group[(74.19±4.53)%vs(64.91±4.78)%,(72.39±4.63)%vs(63.24±4.86)%,(60.34±14.51)%vs(49.12±11.28)%],the difference was statistically significant(t=7.718,7.466,3.344,P<0.05).Conclusion Patients with IPF are treated with self-made Huaxian Tongluo Decoction,symptoms are improved,exercise breathing is good,and lung function is enhanced.

关 键 词：特发性肺纤维化 自拟化纤通络方 运动呼吸 肺功能 

分 类 号：R5[医药卫生—内科学]