益气清毒法对肺癌患者舌脉象动态演变干预的客观化研究  

Objective Study about Intervention of Yiqiqingdu Therapy Method on Dynamic Evolution of Tongue Image Characterizations and Pulse Characterization in Patients with Lung Cancer

作　　者：唐晓玲[1] 余涛 熊林楷[3] 梁启军[4] 余炅[1] 王珠 熊墨年[1] TANG Xiao-ling;YU Tao;XIONG Lin-kai;LIANG Qi-jun;YU Jiong;WANG Zhu;XIONG Mo-nian(Jiangxi Provincial Institute of Traditional Chinese Medicine,Nanchang330046;The Department of Respiratory Medicine,The People's Hospital of Xingguo County in Jiangxi Province,Xingguo342400;The Second department of Internal Medicine,Jiangxi Provincial Cancer Hospital,Nanchang330029;The Department of Pulmonary Diseases,The Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine,Nanchang330006)

机构地区：[1]江西省中医药研究院,南昌330046 [2]江西省兴国县人民医院呼吸内科,兴国342400 [3]江西省肿瘤医院内二科,南昌330029 [4]江西中医药大学附属医院肺病科,南昌330006

出　　处：《实用中西医结合临床》2021年第9期1-4,138,共5页Practical Clinical Journal of Integrated Traditional Chinese and Western Medicine

基　　金：江西省卫生和计划生育委员会中医药科研基金项目(编号:2015A082);国家中医药管理局第一批重点研究室-恶性肿瘤益气清毒重点研究室项目[编号:国中医药函(2009)95号];国家中医药管理局—熊墨年全国名老中医药专家传承工作室项目[编号:国中医药人教发(2013)47号]。

摘　　要：目的:分析中晚期肺癌患者在中医益气清毒法干预后舌脉象客观化参数的动态演变,为中医临床客观化诊疗提供参考。方法:将100例中晚期肺癌患者随机分为治疗组和对照组各50例,治疗组给予中医益气清毒综合治疗,对照组给予西医治疗,两组均治疗4个疗程,分别在治疗前、治疗2个疗程后及治疗4个疗程后各采集1次舌脉象参数,观察治疗过程中舌象和脉象参数的变化。结果:(1)舌象变化:治疗组治疗2个疗程后与治疗前相比,润燥指数、厚薄指数、腐腻指数均有明显变化(P<0.05);治疗4个疗程后与治疗前相比,患者的润燥指数、裂纹指数、厚薄指数、腐腻指数具有明显变化(P<0.05);治疗4个疗程后与治疗2个疗程后相比,裂纹和厚薄指数则有明显差异(P<0.05)。对照组治疗2个疗程后和治疗4个疗程后与治疗前相比,润燥指数、裂纹指数、腐腻指数均有明显变化(P<0.05);治疗4个疗程后与治疗2个疗程后相比,润燥指数下降和裂纹指数升高,均有显著差异(P<0.05)。治疗2个疗程后及治疗4个疗程后两组比较,润燥指数、厚薄指数、腐腻指数、裂纹指数均有明显差异(P<0.05)。(2)脉象变化:治疗组治疗2个疗程后及治疗4个疗程后与治疗前相比,患者的h1、U、P明显升高,h3/h1明显降低,差异有统计学意义(P<0.05);治疗4个疗程后与治疗2个疗程后比较,h1、U、h3/h1变化有明显差异(P<0.05)。对照组治疗2个疗程后与治疗前相比,患者的h3/h1明显降低,差异有统计学意义(P<0.05);治疗4个疗程后与治疗前相比,患者的h1、U、P明显升高,h3/h1明显降低,差异有统计学意义(P<0.05);治疗4个疗程后与治疗2个疗程后相比,患者的U升高,存在明显差异(P<0.05)。治疗2个疗程后,两组间U值有显著差异(P<0.05),治疗组比对照组升高更明显;治疗4个疗程后,两组间h1、U、h3/h1有显著差异(P<0.05),治疗组h1、U值升高更明显,h3/h1降低更明显,差异有Objective: T o analyze the dynamic evolution of objective parameters of tongue and pulse image characterizations in patients with advanced lung cancer after the intervention of TCM method of Yiqiqingdu therapy method, so as to provide reference for the clinical objective diagnosis and treatment of Traditional Chinese Medicine. Methods: 100 patients with advanced lung cancer were randomly divided into treatment group and control group, with 50 cases in each group. The treatment group was given Traditional Chinese Medicine Yiqiqingdu comprehensive treatment, and the control group was given western medicine treatment, both groups were treated for 4 courses. Collected the parameters of tongue and pulse image characterizations before treatment, after 2 courses of treatment and after 4 courses of treatment respectively, and observed the changes of tongue and pulse image characterization parameters during the treatment.Results:(1) Changes of tongue image characterization parameters: In the treatment group, after 2 courses of treatment compared with before treatment, the Runzao index, Thickness index and Greasy coating index had significant changes(P <0.05);after 4 courses of treatment compared with before treatment, the Runzao index, Crack index, Thickness index and Greasy coating index had significant changes(P<0.05);after 4 courses of treatment compared with after 2 courses of treatment, the Crack index and Thickness index had significant changes(P<0.05).In the control group, compared with before treatment, the Runzao index, Crack index and Greasy coating index of after 2 courses and after 4 courses of treatment had significant changes(P<0.05);after 4 courses of treatment compared with after 2 courses of treatment, the Runzao index decreased and the Crack index increased, with significant differences(P<0.05). After 2 courses of treatment and after 4 courses of treatment, there were significant differences in Runzao index, Thickness index, Greasy coating index and Crack index between the two groups(P<0.05).(2) Changes

关 键 词：肺癌 益气清毒法 舌象 脉象 

分 类 号：R273[医药卫生—中西医结合]