阻塞性睡眠呼吸暂停低通气综合征患者主观睡眠质量的性别差异及影响因素  

Gender differences and influencing factors of subjective sleep quality in patients with obstructive sleep apnea hypopnea syndrome

作　　者：徐悠 毛洪京[1] 余正和[1] 韩莉[1] 杨莉莉 郑秋梅 丁秀梅 XU You;MAO Hongjing;YU Zhenghe;HAN Li;YANG Lili;ZHENG Qiumei;DING Xiumei(Sleep Disorders Center,Hangzhou Seventh People′s Hospital,Hangzhou310013,China)

机构地区：[1]杭州市第七人民医院睡眠障碍诊疗中心,浙江杭州310013

出　　处：《中国现代医生》2021年第17期85-90,共6页China Modern Doctor

基　　金：浙江省基础公益研究计划项目(LGF20H090004);浙江省杭州市社会发展科研自主申报项目(医疗卫生)(20180533B81)。

摘　　要：目的通过比较男性和女性睡眠呼吸暂停低通气综合征(OSAHS)患者的主观睡眠质量及相关因素,了解OSAHS主观睡眠质量的性别差异及其影响因素。方法纳入2019年1月至2020年5月至我院睡眠障碍科诊断OSAHS的82例男性及31例女性患者,通过量表评估主观睡眠质量(PSQI)、焦虑程度(GAD-7)、抑郁程度(PHQ-9)、躯体症状(PHQ-15)、嗜睡程度(ESS)。结果男性患者的年龄(47.0岁)比女性患者年轻(56.3岁),BMI(27.0 kg/m2)高于女性(24.7 kg/m2),AHI(18.5次/h)高于女性(11.7次/h),最长呼吸暂停时间(48.0 s)高于女性(33.0 s),平均呼吸暂停时间(24.5 s)高于女性(19.0 s),最低血氧饱和度(82.5%)低于女性(86.0%);女性患者主观睡眠质量(PSQI=16分)比男性(PSQI=13分)更差,嗜睡(ESS=5分)不如男性(ESS=7分)明显,两组比较,差异均有统计学意义(P<0.05)。年龄层(B=0.804)、抑郁程度(B=1.314)、躯体症状(B=1.159)能预测男性患者主观睡眠质量,躯体症状(B=3.288)、最长低通气时间(B=0.173)预测女性患者主观睡眠质量。结论OSAHS患者男女性主观睡眠质量存在差异。男性高龄、抑郁情绪、躯体症状多预测更差的主观睡眠质量;女性躯体症状多、最长低通气时间长预测更差的主观睡眠质量。Objective To explore the gender differences and influencing factors of subjective sleep quality in patients with obstructive sleep apnea hypopnea syndrome(OSAHS)by comparing the subjective sleep quality and related factors between male and female patients with OSAHS.Methods Eighty-two male patients and thirty-one female patients diagnosed with OSAHS in Department of Sleep Disorders of our hospital from January 2019 to May 2020 were included in the study.Scales were used to evaluate the subjective sleep quality(PSQI),the anxiety degree(GAD-7),the depression degree(PHQ-9),the physical symptoms(PHQ-15),and the sleepiness degree(ESS).Results The age of male patients(47.0 years old)was younger than that of female patients(56.3 years old);BMI of male patients(27.0 kg/m2)was higher than that of female patients(24.7 kg/m2);AHI of male patients(18.5 times/h)was higher than that of female patients(11.7 times/h);the longest apnea time of male patients(48.0s)was higher than that of female patients(33.0s);the average apnea time of male patients(24.5 s)was higher than that of female patients(19.0 s);the lowest oxygen saturation of male patients(82.5%)was lower than that of female patients(86.0%).The subjective sleep quality of female patients(PSQI=16 scores)was poorer than that of male patients(PSQI=13 scores),and the sleepiness degree of female patients(ESS=5 scores)was not as obvious as that of male patients(ESS=7 scores),with statically significant differences(P<0.05).The age group(B=0.804),the depression degree(B=1.314),and the physical symptoms(B=1.159)could predict the subjective sleep quality of male patients;the physical symptoms(B=3.288)and the longest apnea hypopnea time(B=0.173)could predict the subjective sleep quality of female patients.Conclusion There is difference in subjective sleep quality between male and female patients with OSAHS.The old age,depressive emotion and more physical symptoms of male patients can predict worse subjective sleep quality;more physical symptoms and longer longest apnea hypopnea time

关 键 词：睡眠呼吸暂停低通气综合征 主观睡眠质量 性别差异 躯体症状 

分 类 号：R563.9[医药卫生—呼吸系统]