机构地区:[1]解放军中部战区总医院康复医学科,湖北武汉430010
出 处:《广州中医药大学学报》2021年第7期1401-1406,共6页Journal of Guangzhou University of Traditional Chinese Medicine
摘 要:【目的】观察通督调神针刺法联合康复运动治疗脑卒中恢复期偏瘫肢体运动功能障碍的临床疗效,并探讨其可能的作用机制。【方法】将108例脑卒中恢复期偏瘫患者随机分为观察组和对照组,每组各54例,对照组给予康复运动疗法治疗,观察组在对照组的基础上联合通督调神针刺法治疗,连续治疗4周。治疗4周后,评价2组临床疗效,观察2组患者治疗前后Fugl-Meyer运动功能评定量表(FMA)评分、Berg平衡量表(BBS)评分以及改良Barthel指数(MBI)评分的变化情况,比较2组患者治疗前后血清神经肽Y(NPY)、白细胞介素10(IL-10)的变化情况,并评价2组的安全性。【结果】(1)观察组总有效率为94.44%(51/54),对照组为79.63%(43/54),观察组疗效优于对照组,差异有统计学意义(P<0.05)。(2)治疗后,2组患者的FMA评分、BBS评分和MBI评分均明显改善(P<0.05),且观察组在改善FMA评分、BBS评分和MBI评分方面明显优于对照组,差异有统计学意义(P<0.05)。(3)治疗后,2组患者的血清NPY、IL-10水平均明显改善(P<0.05),且观察组在改善血清NPY、IL-10水平方面明显优于对照组,差异有统计学意义(P<0.05)。(4)2组患者治疗期间均未出现明显不良反应,2组患者的不良反应发生率比较,差异无统计学意义(P>0.05)。【结论】通督调神针刺法联合康复运动治疗脑卒中恢复期偏瘫,能有效提高患者的肢体运动功能,改善平衡能力,提高患者生活质量,其作用机制可能与抑制血清NPY、IL-10表达水平有关。Objective To observe the therapeutic efficacy of governor vessel-promoting and mind-regulating acupuncture therapy combined with rehabilitation exercise for treatment of limb motor dysfunction in hemiplegia patients during stroke recovery,and to explore the possible mechanism.Methods A total of 108 cases of hemiplegia patients during stroke recovery were randomly divided into observation group and control group,54 cases in each group.The control group received rehabilitation exercise therapy,and the observation group received governor vessel-promoting and mind-regulating acupuncture therapy on the basis of the treatment of the control group,the treatment lasting 4 continuous weeks.After 4 weeks of treatment,the clinical efficacy in the two groups was evaluated.Before and after treatment,changes in Fugl-Meyer motor function rating scale(FMA),berg balance scale(BBS),and modified Barthel index(MBI)in the two groups were evaluated,and serum levels of neuropeptide Y(NPY)and interleukin(IL)-10 were detected by enzyme-linked immunosorbent assay.And the safety of the two groups was evaluated.Results(1)The total effective rate was 94.44%(51/54)in the observation group,and 79.63%(43/54)in the control group.The therapeutic effect of the observation group was superior to that of the control group(P<0.05).(2)After treatment,the FMA,BBS and MBI scores in the two groups were significantly improved(P<0.05),and the improvement in FMA,BBS and MBI scores of the observation group was superior to that of the control group(P<0.05).(3)After treatment,the serum levels of NPY and IL-10 in the two groups were significantly improved(P<0.05),and the improvement in serum levels of NPY and IL-10 of the observation group was superior to that of the control group(P<0.05).(4)No significant adverse reactions were found in the two groups during treatment.There was no significant difference in incidence of adverse reactions between the two groups(P>0.05).Conclusion Governor vessel-promoting and mind-regulating acupuncture therapy combined with reha
关 键 词:通督调神针刺法 康复运动 脑卒中恢复期 偏瘫 肢体运动功能障碍 临床观察
分 类 号:R246.9[医药卫生—针灸推拿学]
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