东垣针法联合枸橼酸莫沙必利治疗妇科腹部术后胃瘫的临床观察  

Clinical Observation of Dongyuan Acupuncture Combined with Mosapride Citrate for Treatment of Gastroparesis after Gynecological Abdominal Surgery

作　　者：张丽敏[1] 管莉文 张永顺 杜伟[1] ZHANG Li-Min;GUAN Li-Wen;ZHANG Yong-Shun;DU Wei(Tangshan Hospital of Traditional Chinese Medicine,Tangshan 063000 Hebei,China;Laoting Maternal and Child Health Care Hospital,Laoting 063600 Hebei,China;Laoting County Hospital of Traditional Chinese Medicine,Laoting 063600 Hebei,China)

机构地区：[1]唐山市中医医院,河北唐山063000 [2]乐亭县妇幼保健院,河北乐亭063600 [3]乐亭县中医医院,河北乐亭063600

出　　处：《广州中医药大学学报》2021年第8期1645-1650,共6页Journal of Guangzhou University of Traditional Chinese Medicine

基　　金：河北省中医药管理局中医药类科研计划资助项目(编号:2017267)。

摘　　要：【目的】观察东垣针法联合枸橼酸莫沙必利治疗妇科腹部术后胃瘫的临床疗效,并观察其对胃肠激素的影响。【方法】将68例妇科腹部术后胃瘫患者随机分为观察组和对照组,每组各34例,对照组给予枸橼酸莫沙必利片治疗,观察组在对照组治疗的基础上给予东垣针法治疗,2组均治疗7 d。治疗7 d后,观察2组患者胃肠动力恢复时间、胃管拔除时间和首次进食时间,比较2组患者治疗前后血清胃动素(MTL)与胃泌素(GAS)含量以及胃电图参数的变化情况,并评价2组的临床疗效。【结果】(1)研究过程中,观察组失访1例,对照组失访2例。最终观察组33例、对照组32例纳入疗效统计。(2)治疗后,观察组的胃管拔除时间、首次进食时间和胃肠动力恢复时间均明显优于对照组,差异有统计学意义(P<0.05)。(3)治疗后,2组患者胃肠电节律紊乱、反应面积、平均频率均明显改善(P<0.05),且观察组在改善胃肠电节律紊乱、反应面积、平均频率方面明显优于对照组,差异有统计学意义(P<0.05)。(4)治疗后,2组患者MTL、GAS水平均明显改善(P<0.05),且观察组在改善MTL、GAS水平方面明显优于对照组,差异有统计学意义(P<0.05)。(5)观察组总有效率为90.91%(30/33),对照组为75.00%(24/32)。观察组疗效优于对照组,差异有统计学意义(P<0.05)。【结论】东垣针法联合枸橼酸莫沙必利治疗妇科腹部术后胃瘫,能明显改善患者临床症状,加速胃肠动力恢复,调节胃肠激素的分泌,疗效显著。Objective To observe the clinical efficacy of Dongyuan acupuncture combined with mosapride citrate for the treatment of gastroparesis after gynecological abdominal surgery,and to observe its effect on gastrointestinal hormones. Methods Sixty-eight patients with gastroparesis after gynecological abdominal surgery were randomly divided into observation group and control group, 34 cases in each group. The control group was treated with mosapride citrate,and the observation group was treated with Dongyuan acupuncture on the basis of the treatment of the control group. Both groups were treated for 7 days. After 7 days of treatment, the recovery time of gastrointestinal motility, the time to gastric tube removal and the time to first eating of the two groups were observed. The changes of serum motilin(MTL)and gastrin(GAS)levels and electrogastrogram parameters were compared between the two groups before and after treatment, and the clinical efficacy of the two groups was evaluated. Results(1)During the trial,one case was lost to follow-up from the observation group and 2 cases from the control group. Finally,33 cases in the observation group and 32 cases in the control group were completed the trial.(2)After treatment,the time to gastric tube removal,the time to first eating and the recovery time of gastrointestinal motility in the observation group were significantly superior to those in the control group,and the difference was statistically significant(P < 0.05).(3)After treatment, the gastrointestinal electric rhythm disorder,reaction area and average frequency of the two groups were significantly improved(P < 0.05),and the observation group was significantly better than the control group in improving gastrointestinal electric rhythm disorder,reaction area and average frequency,and the difference was statistically significant(P < 0.05).(4)After treatment, the levels of MTL and GAS of the two groups were significantly improved(P < 0.05), and the observation group was significantly better than the control group in imp

关 键 词：东垣针法 枸橼酸莫沙必利 胃瘫 胃电图 妇科腹部术后 

分 类 号：R246.9[医药卫生—针灸推拿学]