四逆散证病机量化分析  

Quantitative Analysis of the Pathogenesis of Sini Powder Syndrome

作　　者：吴美燕[1] 冯嘉树 邓志远 刘敏[2] WU Mei-Yan;FENG Jia-Shu;DENG Zhi-Yuan;LIU Min(Guangzhou University of Chinese Medicine,Guangzhou 510405 Guangdong,Cliina;The First Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangzhou 510405 Guangdong,China)

机构地区：[1]广州中医药大学,广东广州510405 [2]广州中医药大学第一附属医院,广东广州510405

出　　处：《广州中医药大学学报》2021年第8期1740-1744,共5页Journal of Guangzhou University of Traditional Chinese Medicine

基　　金：国家自然科学基金项目(编号:81373767);广州中医药大学一流大学和一流学科建设基金项目(编号:A1-2606-19-110-003)。

摘　　要：【目的】量化分析四逆散的配伍特点并深入挖掘四逆散证的病机。【方法】将《伤寒论》所载经方纳入数据库中,采用分别记录的原则处理药物的剂量与炮制方法的差异问题;运用双层频权剪叉算法,计算每味药物的功效权值,进而计算出四逆散的功效权值并判定其功效强度,最后归纳四逆散证的病机特点。【结果】四逆散的Ⅲ级功效为疏肝、止痛;Ⅱ级功效为升阳;Ⅰ级功效为行气、止汗、清热、治心悸;-Ⅰ级功效为益胃、和胃、潜阳、发汗、燥湿、利水、化湿;-Ⅱ级功效为降气。【结论】四逆散证病机为枢机不利、阳郁不达,病位在少阴,治之在厥阴。Objective To quantitatively analyze the compatibility characteristics of Sini Powder and to further explore the pathogenesis of Sini Powder syndrome. Methods The information of the prescriptions contained in Treatise on Febrile Diseases was firstly input into the database,and the differences of the dosage of herbs and the methods for herbal processing were recorded separately. Secondly, the double-layer frequency weight pruning algorithm method was applied to calculate the efficacy weight of each herb. After that,we calculated the efficacy weight of Sini Powder,and then their efficacy intensity was determined. Finally,the pathogenesis characteristics of Sini Powder syndrome was summarized. Results For Sini Powder,the level Ⅲ efficacies were characterized by soothing the liver and relieving pain,the level Ⅱ efficacies were characterized by elevating yang,the level Ⅰefficacies were characterized by activating qi, arresting sweating, clearing heat and treating palpitations, the level-Ⅰefficacies were characterized by tonifying the stomach,regulating the stomach,subsiding yang,inducing diaphoresis, drying dampness, inducing diuresis and dissipating dampness, and the level-Ⅱ efficacies were characterized by descending qi. Conclusion The pathogenesis of Sini Powder syndrome is characterized by the dysfunction of the pivot and stagnation of yang. The disease of Sini Powder syndrome is located in Shaoyin,and the treatment should be aimed at Jueyin.

关 键 词：《伤寒论》 四逆散证 量化分析 病机 方剂 

分 类 号：R289.5[医药卫生—方剂学]