板门穴联合四缝穴点刺治疗小儿功能性消化不良的临床观察  

Clinical Efficacy of Pricking at Sifeng(EX-UE19)and Banmen on Functional Dyspepsia in Children

作　　者：李云海 文希[2] 吴杰妍 LI Yunhai;WEN Xi;WU Jieyan(Third Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine,Guangzhou 510000,Guangdong,China;Guangdong Second Hospital of Traditional Chinese Medicine,Guangzhou 510000,Guangdong,China)

机构地区：[1]广州中医药大学第三附属医院,广东广州510000 [2]广东省第二中医院,广东广州510000

出　　处：《辽宁中医杂志》2021年第4期170-173,共4页Liaoning Journal of Traditional Chinese Medicine

基　　金：国家自然科学基金青年基金(81704172)。

摘　　要：目的明确板门穴联合四缝穴点刺治疗小儿功能性消化不良的临床疗效。方法将90例小儿功能性消化不良患者随机分为对照组、观察组,每组45例。对照组给予常规治疗;观察组给予四缝穴联合板门穴点刺治疗,两组均治疗4周。分别于治疗前、治疗后、随访2周、随访4周评价小儿疳证证候积分,于治疗前、治疗后检测血清中肿瘤坏死因子-α(TNF-α)、白细胞介素-10(IL-10)、胃动素(MTL)的表达,并进行临床疗效评定。结果治疗后两组小儿疳证证候积分及均较治疗前有明显改善(P<0.01),且观察组优于对照组(P<0.01);两组随访2周时积分均优于本组治疗后(P<0.05),且观察组优于对照组(P<0.01);两组随访4周时积分与本组随访2周时积分无明显差异,但观察组随访4周时积分优于对照组(P<0.01)。治疗后两组TNF-α、IL-10、MTL水平均较治疗前有明显改善(P<0.01),且观察组优于对照组(P<0.01)。对照组总有效率为77.7%,治疗组总有效率为93.3%,卡方统计显示两组有效率存在显著统计学差异,观察组优于对照组(P<0.05)。结论本研究发现四缝穴联合板门穴点刺治疗小儿功能性消化不良,可明显降低小儿疳证证候积分,调节炎症因子及胃肠激素表达,值得临床推广应用。Objective To evaluate the clinical efficacy of pricking at Sifeng(EX-UE19)and Banmen on functional dyspepsia in children.Methods A total of 90 children with functional dyspepsia were randomly divided into control group and observation group,with 45in each group.The children in the control group were treated by conventional treatment,and those in the observation group treated by pricking at Sifeng(EX-UE19)and Banmen.The course of treatment was 4 weeks for both groups.The infantile malnutrition syndrome score was assessed before and after treatment as well as after 2and 4 weeks follow-up.TNF-α,IL-10 and MTL were assessed beforeand after treatment.The clinical efficacy was evaluated after treatment.Results After treatment,the total infantile malnutrition syndrome score of both groups were significantly decreased in comparison with those before treatment(P<0.01),and the observation group's was lower than that of the control group(P<0.01).At 2 weeks follow-up,the total infantile malnutrition syndrome score of both groups were significantly decreased in comparison with those aftertreatment(P<0.05),and the observation group's was lower than that of the control group(P<0.01).At 4 weeks follow-up,no significance was found between the two groups on the total infantile malnutrition syndrome score,however,the observation group's was still lower than that of the control group(P<0.01).After treatment,the levels of TNF-α,IL-10 and MTL in both groups were significantly improved in comparison with those before treatment(P<0.01),and the observation group's was lower than that of the control group(P<0.01).The efficacy rate was 77.7%in control group and 93.3%in observation group.The observation group's was higher than that of the control group(P<0.05).Conclusion Pricking at Sifeng(EX-UE19)and Banmen could significantly decrease infantile malnutrition syndrome score and regulate the expressions of TNF-α,IL-10 and MTL,which is worthy of clinical application.

关 键 词：四缝穴 板门穴 点刺 功能性消化不良 小儿 疗效 

分 类 号：R246.4[医药卫生—针灸推拿学]