红细胞分布宽度在急性胰腺炎严重程度中的评估价值  

作　　者：陈南[1] 金钧[1] 

机构地区：[1]苏州大学附属第一医院,215006

出　　处：《浙江临床医学》2021年第7期1004-1006,共3页Zhejiang Clinical Medical Journal

摘　　要：目的探讨红细胞分布宽度(RDW)在急性胰腺炎(AP)疾病严重程度中的评估价值方法527例AP患者分为轻症AP(MAP),中度重症AP(MSAP),重症AP(SAP)三组,分析三组患者的基本临床资料,通过二分类Logistic回归分析得出发生SAP的独立危险因素,绘制ROC曲线,分析RDW对发生SAP的预测价值.结果三组患者白蛋白、红细胞压积、RDW、APACHE Ⅱ评分、Ranson评分、氧合指数比较差异均有统计学意义(P<0.05)。二分类Logistic回归分析结果显示,RDW、APACHE Ⅱ评分及氧合指数均为发生SAP的独立危险因素(P<0.05)。ROC曲线分析显示,RDW曲线下面积为0.903(95%CI 0.938-0.973,P<0.001),APACHE Ⅱ评分为0.875(95%CI 0.812〜0.917,P<0.001),氧合指数为0.871(95%CI0.784〜0-834,P=0.001)结论RDW是发生SAP的独立危险因素,RDW对AP患者疾病严重程度具有良好的判断价值.Objective To explore the value of red blood cell distribution width(RDW)in assessment of the severity of acute pancreatitis(AP).Methods 527 AP patients were divided into mild acute pancreatitis(MAP)group、moderately severe acute pancreatitis(MSAP)group and severe acute pancreatiris(SAP)group.By analyzing the basic clinical data of three groups of patients,the risk factors of happening SAP were classified by binary logistic regression analysis.RDW predictive value of happening SAP was analyzed by drawing ROC curve.Results The differences of albumin,hematocrit,RDW,APACHE Ⅱ score,Ranson score and oxygenation index between three groups were statistically significant(P<0.05).Bin«iry classification logistic regression analysis showed that RDW,APACHE Ⅱ score and oxygenation index were independent risk factors for happening SAP(P<0.05).ROC curve analysis showed that the area under the curve of RDW was 0.903(95%Cl 0.938~0.973,P=0.000),APACHE Ⅱ score was 0.875(95%Cl 0.812-0.917,P=0.000),and oxygenation index was 0.871(95%CI0.784-0-834,P=0.001).Conclusion RDW is an independent predictor of prognosis for happening SAP,and has good judgment value in assessment of the severity of AP.

关 键 词：红细胞分布宽度 急性胰腺炎 ROC曲线 

分 类 号：R54[医药卫生—心血管疾病]