连续性肾脏替代治疗对严重脓毒症患儿维生素B_(1)的影响  

Influence of Continuous Renal Replacement Therapy on Vitamin B_(1) in Children with Severe Sepsis

作　　者：陈晨[1] 金志鹏[1] 王琪[1] 苏军[1] 崔利丹 CHEN Chen;JIN Zhipeng;WANG Qi;SU Jun;CUI Lidan(PICU,the Children's Hospital Affiliated to Zhengzhou University,Zhengzhou 450053,China)

机构地区：[1]郑州大学附属儿童医院内科监护室,河南郑州450053

出　　处：《临床医学工程》2021年第7期887-888,共2页Clinical Medicine & Engineering

基　　金：2018年河南省医学科技攻关计划项目(项目编号:2018020697)。

摘　　要：目的分析连续性肾脏替代治疗对严重脓毒症患儿维生素B1的影响。方法选择2017年3月至2020年3月我院PICU住院的40例严重脓毒症患儿,实施连续性肾脏替代治疗,根据患儿维生素B_(1)皮试结果分为A组(10例,维生素B_(1)肌肉注射)、B组(15例,连续3 d维生素B_(1)肌肉注射)、C组(15例,无维生素B_(1)治疗)。对比三组患儿治疗前后的维生素B1含量及治疗效果。结果B组治疗后第3 d、第7 d的维生素B1含量高于A组与C组(P<0.05)。B组的总有效率高于A组与C组(P<0.05)。结论严重脓毒症患儿在连续性肾脏替代治疗后立即接受连续3 d维生素B_(1)补充治疗,能够有效提高维生素B_(1)含量,提升治疗效果。Objective To analyze the influence of continuous renal replacement therapy on vitamin B1 in children with severe sepsis.Methods 40 children with severe sepsis admitted to our PICU from March 2017 to March 2020 were selected and given continuous renal replacement therapy.According to the results of vitamin B_(1) skin test,they were divided into group A(10 cases,intramuscular injection of vitamin B_(1)),group B(15 cases,continuous three-day intramuscular injection of vitamin B_(1)),and group C(15 cases,without vitamin B_(1) treatment).The vitamin B1 content before and after treatment,and the treatment effect were compared among the three groups.Results The vitamin B_(1) content at third day and seventh day after treatment of group B were higher than those of group A and group C(P<0.05).The total effective rate of group B was higher than those of group A and group C(P<0.05).Conclusions Continuous three-day vitamin B_(1) supplementary treatment after continuous renal replacement therapy for children with severe sepsis can effectively improve the vitamin B_(1) content,and improve the treatment effect.

关 键 词：严重脓毒症 连续性肾脏替代治疗 维生素B_(1) 

分 类 号：R720.597[医药卫生—急诊医学]