Joint effects of Penta-BDE and heavy metals on Daphnia magna survival,its antioxidant enzyme activities and lipid peroxidation  

作　　者：Baohua TANG Lingyan ZHU Qixing ZHOU 

机构地区：[1]Key Laboratory of Pollution Processes and Environmental Criteria(Ministry of Education),Tianjin Key Laboratory of Environmental Remediation and Pollution Control,College of Environmental Science and Engineering,Nankai University,Tianjin 300071,China [2]Key Laboratory of Terrestrial Ecological Process,Institute of Applied Ecology,Chinese Academy of Sciences,Shenyang 110016,China

出　　处：《Frontiers of Environmental Science & Engineering》2011年第1期99-110,共12页环境科学与工程前沿（英文）

基　　金：This work was supported by the National Natural Science Foundation of China(Grant No.20777040);the Ministry of Education,People’s Republic of China as a cultivation fund of the Key Scientific and Technical Innovation Project(No.707011);the specialized research fund for doctoral program of higher education(No.20070055031);the program of New Century Excellent Talent.

摘　　要：The joint toxicity of Penta-BDE(Pe-BDE)and heavy metals including cadmium and copper on Daphnia magna(D.magna)was evaluated on the basis of determining the 48 h survival,antioxidative enzyme responses,and lipid peroxidation.The response was classified as additive,greater than additive,or less than additive by comparing the measured“toxic units,TU”with one.Based on the survival of D.magna,less-than-additive interactions were found in most of mixtures treatments.This may be attributed to the different toxicity mechanism between Pe-BDE and metals.Cu and Cd played a greater role in toxicity than what Pe-BDE did.As for the superoxide dismutase(SOD)and catalase(CAT)activity,most response was less than additive.For the glutathione S-transferases(GST)activity,most of the greater-thanadditive responses were found in the Cu plus Pe-BDE treatments,but the additive responses occurred in Cd plus Pe-BDE treatments and binary metal treatments.For lipid peroxide levels,which were measured as malondialdehyde(MDA)levels,less-than-additive response occurred in the 50%Cd plus 50%Cu and ternary mixture treatments.Results suggested that Pe-BDE,Cd,and Cu could induce different patterns of antioxidant enzyme responses,such as antioxidant/prooxidant responses,depending on their capability to produce reactive oxygen species and antioxidant enzymes to detoxify them.

关 键 词：polybrominated diphenyl ethers(PBDEs) heavy metal mixture toxicity toxic units(TUs) antioxidant enzyme lipid peroxidation 

分 类 号：TG1[金属学及工艺—金属学]