细节干预护理在分子靶向治疗非小细胞肺癌所致皮疹中的应用  

Application of Detailed Nursing Intervention in the Treatment of Skin Rash Caused by Molecular Targeted Therapy for Non-small Cell Lung Cancer

作　　者：陈艳[1] 杨雪 王华[1] 江雪梅 程平[1] Chen Yan;Yang Xue;Wang Hua;Jiang Xuemei;Cheng Ping(Sichuan Cancer Hospital, Chengdu 610041, China)

机构地区：[1]四川省肿瘤医院,成都610041

出　　处：《成都医学院学报》2021年第4期516-519,共4页Journal of Chengdu Medical College

基　　金：四川省科技厅应用基础研究计划项目(No:2016YFS0315)。

摘　　要：目的分析细节干预护理在分子靶向治疗非小细胞肺癌(NSCLC)所致皮疹中的效果。方法选取2015年7月至2019年12月在四川省肿瘤医院接受分子靶向治疗的NSCLC患者90例为研究对象,根据不同干预方式分为试验组和对照组,每组45例。对照组给予常规护理,试验组予以细节干预护理。观察两组皮疹康复情况,采用焦虑自评量表(SAS)、抑郁自评量表(SDS)、健康状况调查量表(SF-36)比较两组心理状态;同时比较两组满意度情况。结果试验组皮疹康复优良率明显高于对照组(P<0.05)。两组干预前SAS、SDS、SF-36评分比较差异无统计学意义(P>0.05);两组干预后SAS及SDS评分下降,试验组干预后SAS及SDS评分下降程度均较对照组明显(P<0.05)。两组干预后SF-36中躯体疼痛评分较干预前下降,而生理职能、生理功能、社会功能、情感职能、精神健康、总体健康、精力7个维度评分均高于干预前,且试验组明显高于对照组(P<0.05)。试验组患者满意度明显高于对照组患者(P<0.05)。结论细节干预护理可提升接受分子靶向治疗NSCLC患者的健康状态,促进皮疹恢复,并对患者心理状态具有积极影响,患者满意度较高。Objective To analyze the effect of detailed nursing intervention in the treatment of skin rash caused by molecular targeted therapy for non-small cell lung cancer(NSCLC).Methods A total of 90 NSCLC patients who received molecular targeted therapy in Sichuan Cancer Hospital from July 2015 to December 2019 were selected as the research objects.According to different intervention methods,they were divided into the experimental group(n=45)and the control group(n=45).The control group received routine nursing care,while the experimental group was given detailed nursing intervention.The rash recovery of the two groups was observed.The psychological status of patients in both groups were compared by using self-rating anxiety scale(SAS),self-rating depression scale(SDS),and the MOS item short from health survey(SF-36).Patient satisfaction was also compared.Results The excellent and good rate of skin rash recovery in the experimental group was significantly higher than that in the control group(P<0.05).Before intervention,there was no significant difference between the two groups in SAS,SDS,and SF-36 scores(P>0.05).After intervention,SAS and SDS scores of both groups decreased,and they decreased more significantly in the experimental group than in the control group(P<0.05).Among items in SF-36,physical pain in both groups decreased after intervention,while physiological function,biological function,social function,emotional function,mental health,general health,and energy scores of both groups after intervention were higher than those before intervention,and those in the experimental group were significantly higher than that in the control group(P<0.05).Patient satisfaction in the experimental group was significantly higher than that in the control group(P<0.05).Conclusion Detailed nursing intervention for NSCLC patients undergoing molecular targeted therapy can improve their health status,promote the recovery of rash,exert a positive impact on their psychological status,and lead to high patient satisfaction.

关 键 词：细节干预护理 分子靶向治疗 非小细胞肺癌 皮疹 

分 类 号：R473.73[医药卫生—护理学]