子宫动脉栓塞术对子宫瘢痕妊娠患者卵巢功能的影响  

Effect of uterine artery embolization on ovarian function in patients with uterine scar pregnancy

作　　者：李涛[1] 谢志江[2] 成艳梅[1] 黄晓青 王春丽[1] 杨新顺[3] 张莉华[1] LI Tao;XIE Zhijiang;CHENG Yanmei;HUANG Xiaoqing;WANG Chunli;YANG Xinshun;ZHANG Lihua(Department of Gynecology,Handan Central Hospital,Handan 056001,China;不详)

机构地区：[1]邯郸市中心医院妇科,河北邯郸056001 [2]邯郸市第一医院妇科,河北邯郸056004 [3]邯郸市中心医院介入科,河北邯郸056001

出　　处：《实用医学杂志》2021年第14期1842-1845,共4页The Journal of Practical Medicine

基　　金：2019年邯郸市科技专项计划项目(编号:19422083009⁃10)。

摘　　要：目的探讨子宫动脉栓塞术对子宫瘢痕妊娠治疗后患者卵巢功能的影响。方法收集2012年1月至2016年12月在邯郸市中心医院就诊年龄<40岁的子宫瘢痕妊娠患者,随机分为子宫动脉栓塞术组(研究组)和其他方法治疗组(对照组),每组各92例。术后随访3年,定期监测两组患者的月经周期长度、促卵泡生成素(FSH)、雌二醇(E2)、卵巢窦状卵泡数,并进行统计学分析。结果子宫动脉栓塞组中月经周期、FSH、E2、卵巢窦狀卵泡数在治疗结束的第6个月分别为(30.12±3.05)d、(5.10±1.08)IU/L、(55.00±11.07)pg/mL、(5.89±1.47)个,第12个月分别为(29.97±1.98)d、(5.24±1.14)IU/L、(58.35±12.23)pg/mL、(5.65±1.67)个,第24个月分别为(30.17±1.73)d、(5.43±1.25)IU/L、(57.67±10.87)pg/mL、(5.51±1.77)个,第36个月分别为(29.78±2.1)d、(5.42±1.29)IU/L、(59.00±12.07)pg/mL、(5.61±1.65)个,各时间段比较差异无统计学意义(均P>0.05)。结论子宫动脉栓塞术治疗子宫瘢痕妊娠与其它治疗方法比较不会引起患者3年内的卵巢功能及月经周期的变化。Objective To investigate the effect of uterine artery embolization on ovarian function of patients with scar pregnancy.Methods From January 2012 to December 2016,patients with uterine scar pregnancy aged less than 40 years in Handan central hospital were randomized into the uterine artery embolization group(study Group)and other methods treatment group(control group),92 cases in each group.The patients were followed up for 3 years.The menstrual cycle length,follicle stimulating hormone(FSH),estradiol(E2)and the number of ovarian antral follicles of the two groups were regularly monitored and analyzed.Result In UAE group,the number of menstrual cycle,FSH,E2 and ovarian antral follicles were(30.12±3.05)days,(5.10±1.08)IU/L,(55.00±11.07)pg/mL and(5.89±1.47)in the 6th month,(29.97±1.98)days,(5.24±1.14)IU/L,(58.35±12.23)pg/mL and(5.65±1.67)in the 12th month,(30.17±1.73)days,(5.43±1.25)IU/L,(57.67±10.87)pg/mL and(5.51±1.67)in the 24th month,and(29.78±2.1)days,(5.42±1.29)IU/L,(59.00±12.07)pg/mL,and(5.61±1.65)in the 36th month after treatment,respectively.There was no significant difference in each period(all P>0.05).Conclusion Uterine artery embolization in the treatment of scar pregnancy and other treatment methods will not cause ovarian function and menstrual cycle changes in 3 years.

关 键 词：子宫动脉栓塞术 子宫瘢痕妊娠 月经周期 促卵泡生成素 卵巢窦状卵泡数 

分 类 号：R714.22[医药卫生—妇产科学]