Difference Analysis of Secondary Metabolites of Herba Polygoni Chinensis from Guangxi  

作　　者：Anda WEI Hua ZHU Fengfeng XIE Miao ZHANG Piaoling HUANG Wenqi YANG 

机构地区：[1]Guangxi University of Chinese Medicine, Nanning 530200, China

出　　处：《Medicinal Plant》2021年第3期21-23,35,共4页药用植物：英文版

基　　金：Development of Huotanmu Capsules,a New Zhuang Drug for Hepatitis B(20183046-1);Collaborative Innovation Center of Zhuang and Yao Ethnic Medicine(Gui Jiao Ke Yan[2013]20);Guangxi Key Laboratory of Zhuang and Yao Ethnic Medicine(Gui Ke Ji Zi[2014]32);Key Discipline of Guangxi:Science of Zhuang Medicine(Gui Jiao Ke Yan[2013]16);First-class Discipline of Guangxi:Ethnopharmacology(Gui Jiao Ke Yan[2018]12).

摘　　要：[Objectives]The differences in secondary metabolites of Herba Polygoni Chinensis from Guangxi were analyzed,in order to find flavonoids which can antagonize liver injury and provide a basis for the quality evaluation of Herba Polygoni Chinensis.[Methods]UPLC-MS was used to analyze the secondary metabolites of Herba Polygoni Chinensis,and emphasis was placed on flavonoids.[Results]Flavonoids were abundant in the secondary metabolites of Herba Polygoni Chinensis.Quercitrin,catechin gallate,epicatechin gallate,hyperoside and so on were screened as the components with high content and antagonistic effect on liver injury.[Conclusions]Quercitrin was the flavonoid compound with the highest content among the three origins.It is stable and has a good protective effect on liver,which is representative.Quercitrin can be considered as the target component to be used as an important index for quality evaluation of Herba Polygoni Chinensis.

关 键 词：Herba Polygoni Chinensis UPLC-MS Secondary metabolite Flavonoid QUERCITRIN 

分 类 号：R28[医药卫生—中药学]