Acupuncture versus oral medicine for women with diminished ovarian reserve:A cohort study  

针刺与药物对卵巢储备功能低下患者生殖激素的影响:前瞻性队列研究

作　　者：Zhi-yi XIONG Yang WANG Xiao-xu LIU Shu-dan YU Yan-hong LI Xin-min LIU Zhi-shun LIU 熊芝怡;王扬;刘晓旭;俞舒丹;李艳红;刘新敏;刘志顺(北京中医药大学,北京100029;中国中医科学院广安门医院针灸科,北京100053;中国中医科学院广安门医院妇科,北京100053)

机构地区：[1]Beijing University of Chinese Medicine,Beijing 100029,China [2]Acupuncture Department,Guang’anmen Hospital,China Academy of Chinese Medical Sciences,Beijing 100053,China [3]Gynecology Department,Guang’anmen Hospital,China Academy of Chinese Medical Sciences,Beijing 100053,China

出　　处：《World Journal of Acupuncture-Moxibustion》2021年第3期176-180,共5页世界针灸杂志（英文版）

基　　金：Supported by the

摘　　要：Objective:To observe whether electro-acupuncture(EA) is better in improving hormone levels among women with diminished ovarian reserve(DOR) compared with oral medicine [Chinese herbs with or without hormone replacement therapy(HRT)] that is often used in gynecology clinics in China.Methods:Eligible participants entered the EA group or medication group according to their preferences.Participants in the EA group received EA treatment,and participants the medication group received herbal decoction alone or combined with HRT.Reproductive hormone levels of the participants were tested before and during treatment in both groups.Results:A total of 80 women with DOR were screened and 57 cases were included(29 in the EA group and 28 in the medication group) in the final analysis.The differences in the change from baseline between the EA and medication group in mean follicle-stimulating hormone(FSH) levels were-6.6(95% Cl,-17.03 to 3.72),(P=0.848) and-7.09(95% CI,-15.86 to 1.66),(P=0.539) at weeks 12 and 24,respectively.The proportion of women with regular FSH levels in the EA and medication group was 51.3% vs 32.1% at week 12(P=0.134) and 51.3% vs 25.0% at week 24(P=0.038).Conclusion:EA might influence regulating the levels of FSH,luteinizing hormone(LH),estrogen and the FSH/LH ratio,and no difference was found between the effects of EA and oral medicine in changes of reproductive hormone levels.

关 键 词：Diminished ovarian reserve ELECTRO-ACUPUNCTURE Progesterone capsules PROGYNOVA Chinese herbal medicine Cohort study 

分 类 号：R271.9[医药卫生—中西医结合]