Catellani Reaction: An Enabling Technology for Vicinal Functionalization of Aryl Halides by Palladium(o)/Norbornene Cooperative Catalysis  

作　　者：Sichan Dong Xinjun Luan 

机构地区：[1]Key Laboratory of Synthetic and Natural Functional Molecule of the Ministry of Education,College of Chemistry&Materials Science,Northwest University,Xi’an,Shaanxi 710127,China

出　　处：《Chinese Journal of Chemistry》2021年第6期1690-1705,共16页中国化学（英文版）

基　　金：the National Natural Science Foundation of China(21925108,21672169);the Key Science and Technology Innovation Team of Shaanxi Province(2017KCT-37);the Key Laboratory Project of Xi'an(201805058ZD9CG42)for financial support.

摘　　要：The Catellani reaction,originally discovered by Catellani in 1997,and further developed by Catellani,Lautens and others,has emerged as a powerful strategy for the synthesis of polysubstituted arenes,which would be difficult to access via traditional methods.In this process,both ortho-and/pso-positions of aryl halides could be functionalized simultaneously with different electrophiles and terminating agents under the cooperative catalysis of palladium and norbornene(NBE).This review focuses on the significant progress of such transformations,and the section of typical Catellani reactions is divided into five parts according to the functionalization mode of ortho-C-H bond:alkylation,arylation,amination,acylation or thiolation.

关 键 词：Catellani reaction PALLADIUM Domino reaction C-H activation Vicinal functionalization 

分 类 号：O62[理学—有机化学]