Catalytic Benzylation Reactions: From C-H Bond Activation to C-N Bond Activation  

作　　者：Tianxiao Jiang Hongchi Liu Haocheng Zhang Hanmin Huang 

机构地区：[1]Hefei National Laboratory for Physical Sciences at the Microscale,and Department of Chemistry,University of Science and Technology of China,Hefei,Anhui 230026,China [2]Center for Excellence in Molecular Synthesis of CAS,Hefei,Anhui 230026,China

出　　处：《Chinese Journal of Chemistry》2021年第5期1070-1078,共9页中国化学（英文版）

基　　金：the University of Science and Technology of China and National Natural Science Foundation of China(Grant Nos.21925111,21790333,21702197 and 21672199)for generous and continuous financial support.

摘　　要：Transition-metal mediated activation of inert chemical bonds is an ongoing topic in homogeneous catalysis.In view of the abundance and accessibility of alkylarenes and benzylamines,the use of them as benzyl source in catalytic benzylation reactions via benzylic C-H and C-N bond activation is highly desirable.Indeed,compared with the traditional approaches with benzyl halide as the substrates,benzylation reactions via C-H and C-N bond cleavage provide more efficient,atom-economic strategies to access myriads of synthetically important molecules.In this account,our group's efforts on catalytic benzylation reactions via directed C-H activation,nondirected C-H activation and C-N bond activation are summarized.

关 键 词：BENZYLATION C-H ACTIVATION C-N ACTIVATION RADICALS CATALYSIS 

分 类 号：O64[理学—物理化学]