胰岛素皮下注射治疗对妊娠期糖尿病患者血糖和妊娠结局的影响研究  

Effect of subcutaneous injection of insulin on blood glucose and pregnancy outcome in patients with gestational diabetes mellitus

作　　者：唐振利[1] TANG Zhenli(Department of Obstetrics and Gynecology,Beijing Chuiyangliu Hospital,Beijing 100021,China)

机构地区：[1]北京市垂杨柳医院妇产科,北京100021

出　　处：《中国现代医生》2021年第18期50-53,共4页China Modern Doctor

摘　　要：目的探讨胰岛素皮下注射治疗对妊娠期糖尿病患者血糖和妊娠结局的影响。方法从我院2016年1月至2018年12月选取160例妊娠期糖尿病患者,将患者随机分成两组,每组80例,一组为对照组,采用常规运动饮食治疗。另一组为观察组,在对照组的基础上进行胰岛素皮下注射治疗。观察比较两组患者的血糖情况、产妇不良情况以及新生儿不良事件情况。结果两组患者治疗前,糖化血供蛋白(HbA1c)、餐后2 h血糖(2hPG)、空腹血糖(FBG)无明显差异(P>0.05),治疗后,观察组患者的HbA1c、2hPG、FBG,比对照组更低,两组比较差异有统计学意义(P<0.05)。观察组产妇不良情况发生率11.25%,比对照组26.25%更低,两组比较差异有统计学意义(P<0.05)。观察组新生儿不良事件发生率8.75%,比对照组21.25%更低,两组比较差异有统计学意义(P<0.05)。结论胰岛素皮下注射能够有效控制妊娠期糖尿病患者的血糖水平,改善妊娠结局,减少母婴不良事件。Objective To investigate the effect of insulin through subcutaneous injection on blood glucose and pregnancy outcome in patients with gestational diabetes mellitus(GDM).Methods A total of 160 patients with GDM admitted to our hospital from January 2016 to December 2018 were selected.They were randomly divided into two groups,with 80 cases in each group.The control group was treated with conventional exercise and diet.The observation group was given insulin subcutaneously on the basis of the control group.The blood glucose,maternal adverse conditions and neonatal adverse events were observed and compared between the two groups.Results Before treatment,there were no significant differences in glycosylated hemoglobin(HbA1c),2-hour postprandial blood glucose(2 hPG),and fasting blood glucose(FBG)between the two groups(P>0.05).After treatment,HbA1c,2 hPG,and FBG were lower in the observation group than those in the control group,with significant statistically differences(P<0.05).The incidence of maternal adverse conditions in the observation group was 11.25%,which was lower than that in the control group(26.25%),with significant statistically difference(P<0.05).The incidence of neonatal adverse events in the observation group was 8.75%,which was lower than that in the control group(21.25%),with significant statistically difference(P<0.05).Conclusion The subcutaneous injection of insulin can effectively control the blood glucose level of patients with GDM,improve pregnancy outcome and reduce adverse events of mother and infant.

关 键 词：胰岛素 皮下注射 妊娠期糖尿病 血糖 妊娠结局 

分 类 号：R714.256[医药卫生—妇产科学]