Bentall术对升主动脉瘤患者LVEF、LVEDD的影响  

Intervention effect of Bentall operation on LVEF and LVEDD among patients with ascending aortic aneurysm

作　　者：常明明 刘学刚[1] 施超[1] 刘戈[1] CHANG Ming-ming(Department of cardiac surgery,the first affiliated hospital of Bengbu Medical College,Bengbu,Anhui,233000,China)

机构地区：[1]蚌埠医学院第一附属医院心脏外科,安徽蚌埠233000

出　　处：《齐齐哈尔医学院学报》2021年第11期928-932,共5页Journal of Qiqihar Medical University

基　　金：安徽省科技攻关项目(1804h08020256)。

摘　　要：目的分析升主动脉瘤患者实施Bentall术治疗对左室射血分数(LVEF)及左室舒张末期内径(LVEDD)指标的干预观察。方法选择2016年1月—2019年12月本院收治的升主动脉瘤患者75例作为研究对象,选择奇偶数法分为对照组(常规治疗+美托洛尔,n=40)和观察组(Bentall术,n=35)两组。对比分析两组患者的心功能指标,统计临床指标与并发症发生情况,观察心功能分级与生活质量。结果在LVEF、LVEDD以及左心室收缩末期内径(LVESD)上,观察组优于对照组(P<0.05)。在心输出量(CO)、每搏心输出量(SV)、氨基末端B型利钠肽前体(NT-proBNP)、心脏型脂肪酸结合蛋白(H-FABP)以及半乳糖凝集素-3(Galectin-3)上,观察组优于对照组(P<0.05)。在体外循环时长、主动脉阻断时长、呼吸机辅助时长与住院天数上,观察组短于对照组(P<0.05)。在并发生发生率上,观察组低于对照组(P<0.05)。在心功能分级上,观察组优于对照组(P<0.05)。在生理职能、心理状态、情感职能与社会职能评分上,观察组高于对照组(P<0.05)。结论Bentall术用于升主动脉瘤患者的治疗效果理想,对于心功能的改善具有促进作用,可有效提升临床疗效,临床可进一步推广运用。Objective To analyze the intervention effect of Bentall operation on left ventricular ejection fraction(LVEF)and left ventricular end diastolic diameter(LVEDD)among patients with ascending aortic aneurysm.Methods A total of 75 patients with ascending aortic aneurysm who were treated in our hospital from January 2016 to December 2019 were selected as study subjects and they were divided into control group(conventional treatment+metoprolol,n=40)and experimental group(Bentall operation,n=35).The cardiac function indexes of the two groups of patients were compared and analyzed,the clinical indexes and complications were counted,and the cardiac function classification and quality of life were observed.Results LVEF,LVEDD and left ventricular end systolic diameter(LVESD)in the experimental group were better than those in the control group(P<0.05).Cardiac output(CO),stroke volume(SV),amino-terminal B-type natriuretic peptide precursor(NT-proBNP),heart fatty acid binding protein(H-FABP)and galectin-3(Galectin-3)in the experimental group were better than those in control group(P<0.05).The duration of cardiopulmonary bypass,the duration of aortic occlusion,the duration of ventilator assistance and the number of days in hospital were shorter in the experimental group than in the control group(P<0.05).The incidence of complications in the experimental group was lower than the control group(P<0.05).The classification of cardiac function in the experimental group was better than the control group(P<0.05).The scores of physiological function,mental state,emotional function and social function in the experimental group were higher than the control group(P<0.05).Conclusions Bentall procedure is effective in the treatment of patients with ascending aortic aneurysm,which could promote the improvement of cardiac function,effectively improve the clinical efficacy,and could be further applied in clinic.

关 键 词：升主动脉瘤 BENTALL术 心功能 临床指标 

分 类 号：R654.2[医药卫生—外科学]