Effect of addition of inulin and fenugreek on the survival of microencapsulated Enterococcus durans 39C in alginate-psyllium polymeric blends in simulated digestive system and yogurt  

作　　者：Babak Haghshenas Yousef Nami Minoo Haghshenas Abolfazl Barzegari Simin Sharifi Dayang Radiah Rozita Rosli Norhafizah Abdullah 

机构地区：[1]Institute of Biosciences,University Putra Malaysia,43400 UPM Serdang,Selangor,Malaysia [2]School of Medicine,Shahid Beheshti University of Medical Sciences,Tehran,Islamic Republic of Iran [3]Tabriz University of Medical Sciences,Molecular Medicine and Therapy Lab,Research Center for Pharmaceutical Nanotechnology,Tabriz,Islamic Republic of Iran [4]Chemical and Environmental Engineering Department,Faculty of Engineering,University Putra Malaysia,43400 UPM Serdang,Selangor,Malaysia

出　　处：《Asian Journal of Pharmaceutical Sciences》2015年第4期350-361,共12页亚洲药物制剂科学（英文）

基　　金：supports of the University Putra Malaysia are gratefully acknowledged.

摘　　要：The use of biopolymers for probiotic microencapsulation has been investigated in this paper.The objectives are to enhance its survival rate,colonic release,and stability of these probiotic cultures in digestive condition during storage time.Nine types of biopolymers(alginate-psyllium)blend with different concentration of prebiotic;(inulin or fenugreek)were used as candidate for microencapsulation matrix.One strain of probiotic candidates,namely;Enterococcus durans 39C was used in this study.The microencapsulation of this strain with the respective polymer blend was performed by using a simple extrusion method.All blend of formulations have recorded high encapsulation efficiency at value>98%.The survival rate of viable probiotic cells under simulated digestive conditions was also high with value above 47%as compared to non-microencapsulated cells.These nine gel formulations also displayed the high survival rate of viable probiotic cells during storage time(28 d).Their release occurred after 2 h in colonic condition and sustained until 12th h of incubation period.An increase of prebiotic effect value added was observed in incorporated inulin and fenugreek formulations.In short,this study revealed that a new herbal-based psyllium and fenugreek polymers have suitable potential as a matrix for probiotic microencapsulation.

关 键 词：MICROENCAPSULATION PSYLLIUM FENUGREEK Probiotic Enterococcus durans 39C 

分 类 号：O63[理学—高分子化学]